U8507
Ubiquitin K48R human
≥95% (SDS-PAGE), recombinant, expressed in E. coli, solid
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About This Item
UNSPSC Code:
12352202
MDL number:
biological source
human
recombinant
expressed in E. coli
assay
≥95% (SDS-PAGE)
form
solid
mol wt
8.5 kDa
technique(s)
ligand binding assay: suitable
solubility
aqueous buffer: <10 mg/mL
storage temp.
−20°C
Gene Information
human ... UBB(7314), USP10(9100)
General description
Manufactured for Sigma by Boston Biochem., Inc.
Biochem/physiol Actions
Can form an E1-catalyzed active thioester at the C-terminus allowing the molecule to be transferred to the lysines of substrate proteins (monoubiquitination).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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V Chau et al.
Science (New York, N.Y.), 243(4898), 1576-1583 (1989-03-24)
The ubiquitin-dependent degradation of a test protein beta-galactosidase (beta gal) is preceded by ubiquitination of beta gal. The many (from 1 to more than 20) ubiquitin moieties attached to a molecule of beta gal occur as an ordered chain of