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Merck
CN

V0877

Sigma-Aldrich

Snake venom from Crotalus basiliscus

Synonym(s):

Mexican West-Coast Rattlesnake

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About This Item

UNSPSC Code:
12352200
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storage temp.

−20°C

Application

Snake venom from Crotalus basiliscus (Mexican West-Coast Rattlesnake) may be used as a source of α 2PI (α 2-antiplasmin) degrading and α 2M (α 2-macroglobulin) inhibiting enzymes; fibrinolytic enzyme as well as other toxins. It may also be used as an immunogen or for proteome research.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品
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P Svoboda et al.
Toxicon : official journal of the International Society on Toxinology, 33(10), 1331-1346 (1995-10-01)
Three distinct alpha 2PI (alpha 2-antiplasmin) degrading and alpha 2M (alpha 2-macroglobulin) inhibiting enzymes, named proteinase a, b and c, have been purified from the venom of Crotalus basiliscus (the Mexican west coast rattlesnake) by fast protein liquid chromatography (anion-exchange
A D Retzios et al.
Thrombosis research, 74(4), 355-367 (1994-05-15)
Zinc metalloproteinases with fibrinolytic activity have been isolated from the venom of Agkistrodon contortrix contortrix (fibrolase) and Crotalus basiliscus basiliscus (basiliscusfibrases 1, 2 and 3). Fibrolase cleaves the A alpha-chain of fibrinogen initially at a single site: Lys413-Leu. Basiliscusfibrases 1
A D Retzios et al.
Biochemistry, 31(19), 4547-4557 (1992-05-29)
Three distinct fibrinolytic enzymes have been purified from the venom of Crotalus basiliscus basiliscus (the Mexican west coast rattlesnake). The high-performance liquid chromatography-based purification comprised the following steps: (a) hydrophobic interaction chromatography; (b) hydroxylapatite chromatography; (c) anion-exchange chromatography. Following hydrophobic
G Datta et al.
Archives of biochemistry and biophysics, 317(2), 365-373 (1995-03-10)
Snake venoms, especially from the Crotalidae family, contain a variety of enzymes that prevent blood coagulation by virtue of their fibrinolytic enzymes. Nineteen snake venoms were screened for fibrinolytic activity and the highest activity was found in the venom of

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