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Merck
CN

V2015

Sigma-Aldrich

VU10010

≥98% (HPLC)

Synonym(s):

Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethyl-

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About This Item

Empirical Formula (Hill Notation):
C17H16ClN3OS
CAS Number:
633283-39-3
Molecular Weight:
345.85
UNSPSC Code:
12352209

Key Documents

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Assay

≥98% (HPLC)

form

powder

color

white to off-white

solubility

DMSO: >10 mg/mL

storage temp.

2-8°C

Biochem/physiol Actions

VU10010 is a potent and selective allosteric M4 agonist. It potentiates the response to acetylcholine 47-fold at M4 receptors, but has no effect at other receptor subclasses. It is suspected to have even finer selectivity, operating at excitatory, but not at inhibitory, hippocampal synapses.
VU10010 is an allosteric M4 agonist.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318

Precautionary Statements

P280 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
039K4724

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