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Merck
CN

V2390

Sigma-Aldrich

VRT-532

≥98% (HPLC)

Synonym(s):

4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, CFpot 532

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About This Item

Empirical Formula (Hill Notation):
C16H14N2O
CAS Number:
38214-71-0
Molecular Weight:
250.30
UNSPSC Code:
12352200

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Assay

≥98% (HPLC)

form

solid

solubility

DMSO: >20 mg/mL

storage temp.

−20°C

InChI

1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)

InChI key

AQWKVJFRGORALM-UHFFFAOYSA-N

Biochem/physiol Actions

VRT-532 is a mutated G551D CFTR corrector.
VRT-532 is a mutated G551D CFTR corrector. VRT-532 mediates G551D-CFTR by enhancement of ATP affinity of the mutant. VRT-532 also potentiates F508del mutated CFTR and works specifically on mutant CFTR rather than other membrane proteins.

Features and Benefits

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H318

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
039K4620V
0000066328
039K4620

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