V2390
VRT-532
≥98% (HPLC)
Synonym(s):
4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, CFpot 532
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About This Item
Empirical Formula (Hill Notation):
C16H14N2O
CAS Number:
Molecular Weight:
250.30
UNSPSC Code:
12352200
InChI key
AQWKVJFRGORALM-UHFFFAOYSA-N
InChI
1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)
assay
≥98% (HPLC)
form
solid
solubility
DMSO: >20 mg/mL
storage temp.
−20°C
Biochem/physiol Actions
VRT-532 is a mutated G551D CFTR corrector.
VRT-532 is a mutated G551D CFTR corrector. VRT-532 mediates G551D-CFTR by enhancement of ATP affinity of the mutant. VRT-532 also potentiates F508del mutated CFTR and works specifically on mutant CFTR rather than other membrane proteins.
Features and Benefits
This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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