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WH0114908M2

Sigma-Aldrich

Monoclonal Anti-PORIMIN antibody produced in mouse

clone 1F4, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-KCT3, Anti-pro-oncosis receptor inducing membrane injury gene

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
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biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1F4, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG1κ

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Monoclonal Anti-PORIMIN antibody produced in mouse clone 1F4, purified immunoglobulin, buffered aqueous solution

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Monoclonal Anti-PORIMIN antibody produced in mouse

Anti-TMEM123 antibody produced in mouse purified immunoglobulin, buffered aqueous solution

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Anti-TMEM123 antibody produced in mouse

Monoclonal Anti-EDG1 antibody produced in mouse clone 2E12, purified immunoglobulin, buffered aqueous solution

WH0001901M1

Monoclonal Anti-EDG1 antibody produced in mouse

Monoclonal Anti-TNFRSF6B antibody produced in mouse clone 7G5, purified immunoglobulin, buffered aqueous solution

WH0008771M2

Monoclonal Anti-TNFRSF6B antibody produced in mouse

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

clone

1F4, monoclonal

clone

polyclonal

clone

2E12, monoclonal

clone

7G5, monoclonal

Gene Information

human ... TMEM123(114908)

Gene Information

human ... TMEM123(114908)

Gene Information

human ... S1PR1(1901)

Gene Information

human ... TNFRSF6B(8771)

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

General description

This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. (provided by RefSeq)

Immunogen

TMEM123 (NP_443164, 34 a.a. ~ 133 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
ETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTAASNTTTPGMVSTNMTSTTLKSTPKTTSVSQNTSQISTSTMTVTHNSSVTSAASSVTITT

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
07299-1F4

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