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Merck
CN

WH0154214M1

Monoclonal Anti-IBRDC1 antibody produced in mouse

clone 4B1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-C6orf172, Anti-IBR domain containing 1, Anti-MGC26996, Anti-dJ84N20.1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
4B1, monoclonal
Application:
ELISA (i), IF, WB
Citations:
2

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4B1, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

NM_152553

UniProt accession no.

Q8TC41

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RNF217(154214)

General description

IBR domain containing 1 (IBRDC1) or ring finger protein 217 is expressed in the skeletal muscle and testis. It is made up of 284 amino acids.

Immunogen

IBRDC1 (NP_689766, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KVQLGQVEIKCPITECFEFLEETTVVYNLTHEDSIKYKYFLELGRIDSSTKPCPQCKHFTTFKKKGHIPTPSRSESKYKIQCPTCQFVWCFKCHSPWHE

Biochem/physiol Actions

IBR domain containing 1 (IBRDC1) is expressed in leukemia cells. It has been categorized as an E3 ubiquitin-protein ligase.

Features and Benefits

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Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
07103-4B1

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Luciana M Fontanari Krause et al.
Scientific reports, 4, 6565-6565 (2014-10-10)
Genomic aberrations involving ETV6 on band 12p13 are amongst the most common chromosomal abnormalities in human leukemia. The translocation t(6;12)(q23;13) in a childhood B-cell acute lymphoblastic leukemia (ALL) cell line fuses ETV6 with the putative long non-coding RNA gene STL.
Jieying Li et al.
Marine biotechnology (New York, N.Y.), 13(2), 232-241 (2010-04-17)
Infectious salmon anemia (ISA) has been described as the hoof and mouth disease of salmon farming. ISA is caused by a lethal and highly communicable virus, which can have a major impact on salmon aquaculture, as demonstrated by an outbreak

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