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X1504

Anti-XPA (N-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-XP1, Anti-XPAC, Anti-Xeroderma pigmentosum, complementary group A

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About This Item

UNSPSC Code:
12352203
MDL number:
MFCD09265381

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 35 kDa (doublet)

species reactivity

human

concentration

~1 mg/mL

technique(s)

immunoprecipitation (IP): 5-10 μg using HEK-293T cell lysates, indirect immunofluorescence: 5-10 μg/mL using A549 cells fixed with paraformaldehyde/Triton, western blot: 0.5-1 μg/mL using Jurkat cell lysates

UniProt accession no.

P23025

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... XPA(7507)

General description

XPA (N-terminal), xeroderma pigmentosum, complementation group A, encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-i

Immunogen

synthetic peptide corresponding to amino acids 15-33 of human XPA, conjugated to KLH via a C-terminal added cysteine residue. The immunizing peptide differs from the rat sequence in three amino acids.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
037K4809

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Iltaeg Cho et al.
PLoS genetics, 9(4), e1003407-e1003407 (2013-05-03)
The Cockayne syndrome complementation group B (CSB) protein is essential for transcription-coupled DNA repair, and mutations in CSB are associated with Cockayne syndrome--a devastating disease with complex clinical features, including the appearance of premature aging, sun sensitivity, and numerous neurological

Related Content

Data Sheet - X1504

Instructions

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