Y4377
YEEI Peptide, Phosphorylated trifluoroacetate salt
lyophilized powder
Synonym(s):
(pY)EEI, YEEI Peptide
Assay
≥95% (HPLC)
form
lyophilized powder
mol wt
calculated mol wt 1474.8 Da (free base)
calculated mol wt 1588.8 Da
solubility
H2O: soluble
storage temp.
−20°C
Amino Acid Sequence
Glu-Pro-Gln-Tyr(PO3H2)-Glu-Glu-Ile-Pro-Ile-Tyr-Leu
Biochem/physiol Actions
Used to study the effect of activation of endogenous c-Src tyrosine kinase.
YEEI Peptide is a phosphopeptide that activates Src family members by binding to their SH2 domain with high affinity.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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S Wijetunge et al.
FEBS letters, 399(1-2), 63-66 (1996-12-09)
The effect of activation of endogenous c-Src tyrosine kinase by (pY)EEI peptide was examined on voltage-operated calcium channel (VOC) currents in arterial smooth muscle cells. In single rabbit ear artery cells intracellular application of (pY)EEI peptide increased calcium channel currents.
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