Z700479
Platelet Protocols: Research and Clinical Laboratory Procedures
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About This Item
publication info
M. White and L. Jennings, Academic Press, 1999, 128 pp., comb bound
manufacturer/tradename
Elsevier
General description
Table of Contents
Introduction.
Variables.
Drawing and Processing Blood for Platelet Aggregation.
Platelet Aggregation and Secretion.
Platelet Agonists.
Clot Retraction.
Functional Abnormalities of Platelets:
Introduction.
Storage Pool Disorders.
Release Defects.
Glanzmann′s Thrombasthenia.
Von Willebrand′s Disease.
Bernard Soulier Syndrome.
Bleeding Time Prolongation.
Therapeutic Approaches to Inhibition of Platelet Function and Pharmacodynamic Evaluations:
GPIIb-IIIa Antagonists.
Other Anti-Platelet Therapies.
Drugs That May Affect Platelet Function.
Appendix:
Recipes for Citrate Based Anticoagulants.
Inhibitors Used in Platelet Techniques.
Cytoskeletal Preparation and Recipes.
Gel-Filtered Platelets.
Washed Platelets.
Western Blots of Acrylamide Gels Gell and Blot Recipes.
Staining of Platelets for Flow Cytometric Analysis.
Subject Index.
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