Z700819
Practice of Medicinal Chemistry, 2nd ed.
an essential handbook for the medicinal chemist - a complete guide to the drug discovery process
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About This Item
ISBN-10:
0-12-744481-5
UNSPSC Code:
55101509
ISBN-13:
978-0-12-744481-9
publication info
C. Wermuth, ed., Academic Press, 2003, 624 pp., hard cover
General description
This is an essential handbook for the medicinal chemist - a complete guide to the drug discovery process.
It reviews practical aspects of Medicinal Chemistry, emphasizing the daily problems when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimizing pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications.
This edition is revised, with around 30% new material, and refocussed to reflect the developments in genomics, proteomics, high throughput screening of compounds and drug solubilization.
It reviews practical aspects of Medicinal Chemistry, emphasizing the daily problems when dealing with lead discovery/identification methodologies, with structure-activity relationship studies aimed to scale up potency and target selectivity, and when optimizing pharmacokinetic and pharmaceutical properties by means of ultimate chemical modifications.
This edition is revised, with around 30% new material, and refocussed to reflect the developments in genomics, proteomics, high throughput screening of compounds and drug solubilization.
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