Modern Methods of Drug Discovery

This volume offers an interdisciplinary view of modern approaches to drug discovery as used by pharmaceutical companies and research institutes. It covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each of the thirteen chapters reviews the theory, background and application of a key technology in drug discovery and is complemented by an extensive list of references to the original literature. The book is written from the viewpoint of the drug researcher working in the pharmaceutical industry and provides an overview of the drug discovery process.