Human Molecular Genetics 3

This book provides a complete account of human molecular genetics in the post-genome era, from basic principles to current practice. It is designed to engage readers with detailed full-color illustrations, special topic boxes (coverage of ethical, legal and social issues) and a constant emphasis on understanding principles rather than memorizing detail. Initial chapters cover DNA structure and function, chromosomes, pedigrees and the basic techniques of PCR, cloning and hybridization, and include a new chapter on cells and development. Later chapters detail new understanding of the structure, organization, expression and evolution of the human genome. Final sections cover functional genomics, the role of animal models and new approaches to genetic treatment of disease.