Boronic Acids: Preparation and Application in Organic Synthesis and Medicine

Dennis Hall covers all aspects of this important substance class. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds.

There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. With experimental procedures, this book is invaluable reading for organic, catalytic and medicinal chemists, and those working in organometallics.