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Merck
CN

40368

1,2,3-Trichloropropane solution

5000 μg/mL in methanol, analytical standard

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About This Item

CAS Number:
96-18-4
UNSPSC Code:
41116105

Key Documents

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InChI key

CFXQEHVMCRXUSD-UHFFFAOYSA-N

InChI

1S/C3H5Cl3/c4-1-3(6)2-5/h3H,1-2H2

grade

analytical standard

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - Repr. 1B - STOT SE 1

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
LB79773
LB66177
LB45000
LB32363
LA84195

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Martina Pavlova et al.
Nature chemical biology, 5(10), 727-733 (2009-08-25)
Engineering enzymes to degrade anthropogenic compounds efficiently is challenging. We obtained Rhodococcus rhodochrous haloalkane dehalogenase mutants with up to 32-fold higher activity than wild type toward the toxic, recalcitrant anthropogenic compound 1,2,3-trichloropropane (TCP) using a new strategy. We identified key
Pavel Banás et al.
Journal of computer-aided molecular design, 20(6), 375-383 (2006-10-04)
1,2,3-Trichloropropane (TCP) is a highly toxic, recalcitrant byproduct of epichlorohydrin manufacture. Haloalkane dehalogenase (DhaA) from Rhodococcus sp. hydrolyses the carbon-halogen bond in various halogenated compounds including TCP, but with low efficiency (k (cat)/K (m )= 36 s(-1) M(-1)). A Cys176Tyr-DhaA
P Liu et al.
Human & experimental toxicology, 31(5), 523-527 (2011-11-03)
1,2,3-trichloropropane (1,2,3-TCP) is commonly used as an intermediate in pesticide and an industrial specialty solvent. Acute 1,2,3-TCP poisoning is rare but a medical emergency. Sporadic cases of toxic hepatic injury from 1,2,3-TCP in humans have been reported. Liver is a
1,2,3-Trichloropropane.
Report on carcinogens : carcinogen profiles, 11, III264-III266 (2004-01-01)
Alena Stsiapanava et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 67(Pt 2), 253-257 (2011-02-09)
Haloalkane dehalogenases make up an important class of hydrolytic enzymes which catalyse the cleavage of carbon-halogen bonds in halogenated aliphatic compounds. There is growing interest in these enzymes owing to their potential use in environmental and industrial applications. The haloalkane
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