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Merck
CN

40567

7,12-Dimethylbenz[a]anthracene solution

certified reference material, 1000 μg/mL in methanol

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About This Item

CAS Number:
57-97-6
PubChem Substance ID:
24865324
UNSPSC Code:
41116105
Beilstein/REAXYS Number:
1912135
MDL number:
MFCD00003600

Key Documents

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SMILES string

Cc1c2ccccc2c(C)c3c1ccc4ccccc34

InChI

1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3

InChI key

ARSRBNBHOADGJU-UHFFFAOYSA-N

grade

certified reference material, TraceCERT®

packaging

ampule of 1 mL

concentration

1000 μg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

Quality Level

100

General description

7,12-Dimethylbenz[a]anthracene is a polyaromatic hydrocarbon, which is a pollutant that can be released into the environment due to incomplete combustion.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

49.5 °F - Methanol

flash_point_c

9.7 °C - Methanol

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

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Bioprotective Efficacy of Erucin Against 7, 12-Dimethylbenz (?) anthracene-Induced Microstructural Changes in Male Wistar Rats
Mannan R, et al.
Turkish Journal of Pathology, 33, 150-156 (2017)
Ramar Perumal Samy et al.
PloS one, 7(12), e48514-e48514 (2013-01-04)
Breast cancer is the most common cancer among women. To date, improvements in hormonal and cytotoxic therapies have not yet led to a sustained remission or cure. In the present study, we investigated the in vitro and in vivo antitumor
Gaurav Kumar et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 31(4), 295-312 (2013-02-12)
In the present study, post-treatment effects of dietary turmeric on markers related to apoptosis, cell proliferation, and inflammation in 7,12-dimethylbenz(a)anthracene (DMBA)-induced hamster buccal pouch (HBP) tumors were investigated. Tumors were induced by applying 0.5% DMBA topically to the HBP three
Jitender Monga et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 31(4), 313-323 (2013-02-12)
The objective of this study was to investigate the chemopreventive potential of (+)-catechin-rich extract of Acacia catechu heartwood (AQCE) against 7,12-dimethylbenz[a]anthracene (DMBA)-induced hepatocellular carcinoma in Balb/c mice. The levels of liver injury markers, tumor markers, and oxidative stress were measured
Peter T Vedell et al.
Molecular pharmacology, 83(3), 698-708 (2013-01-08)
Examination of three retinoid X receptor (RXR) agonists [Targretin (TRG), UAB30, and 4-methyl-UAB30 (4-Me-UAB30)] showed that all inhibited mammary cancer in rodents and two (TRG and 4-Me-UAB30) strikingly increased serum triglyceride levels. Agents were administered in diets to female Sprague-Dawley
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