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Merck
CN

46916-U

Zearalenone solution

50 μg/mL in acetonitrile, analytical standard

Synonym(s):

ZON

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About This Item

Empirical Formula (Hill Notation):
C18H22O5
CAS Number:
17924-92-4
Molecular Weight:
318.36
UNSPSC Code:
85151701
PubChem Substance ID:
24870569
EC Number:
200-835-2
MDL number:
MFCD00133085

Key Documents

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InChI key

MBMQEIFVQACCCH-QBODLPLBSA-N

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

SMILES string

OC1=C(C(O[C@@H](C)CCC2)=O)C(/C=C/CCCC2=O)=CC(O)=C1

grade

analytical standard

CofA

certificate of analysis is enclosed in each package.

packaging

ampule of 1 mL

concentration

50 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

single component solution

storage temp.

−20°C

Gene Information

mouse ... Esr1(13982)

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General description

Zearalenone is a mycotoxin, produced by Fusarium species and often contaminates grains and stored feeds.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Zearalenone was used as standard in microwave-assisted extraction method for determination of zearalenone in wheat and corn by liquid chromatography-mass spectrometry with an atmospheric pressure chemical ionization interface. It was used as analytical standard in determination of zearalenone content of maize, wheat, barley, swine feed and poultry feed samples by immunoaffinity column clean-up followed by liquid chromatography. It may be used as internal standard in simultaneous determination of the type A- and B-trichothecenes as well as zearalenone in maize by high performance liquid chromatography-tandem mass spectrometry.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

42.8 °F - closed cup

flash_point_c

6 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
LB99109
LB89570
LB68737
LB66402
LB66161

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B Fazekas et al.
Journal of AOAC International, 84(5), 1453-1459 (2001-10-17)
The zearalenone content of maize, wheat, barley, swine feed, and poultry feed samples was determined by immunoaffinity column cleanup followed by liquid chromatography (IAC-LC). Samples were extracted in methanol-water (8 + 2, v/v) solution. The filtered extract was diluted with
Lea Pallaroni et al.
Analytical and bioanalytical chemistry, 374(1), 161-166 (2002-09-11)
A microwave-assisted extraction (MAE) method has been developed for determination of zearalenone in wheat and corn by LC-MS with an atmospheric pressure chemical ionization interface (APCI). Matrix effects were minimized by use of matrix-matched standard curves for quantification of the
Franz Berthiller et al.
Journal of chromatography. A, 1062(2), 209-216 (2005-02-01)
A novel method for the simultaneous determination of the Fusarium mycotoxins nivalenol, deoxynivalenol, fusarenon-X, 3-acetyl-deoxynivalenol, the sum of 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol, diacetoxy-scirpenol, HT-2 toxin, T-2 toxin and zearalenone in maize has been developed using gradient RP-LC with atmospheric pressure chemical
Feng Gao et al.
Mutation research, 755(1), 6-10 (2013-05-07)
Mycotoxins are considered to be significant contaminants of food and animal feed. Zearalenone (ZEA) is a hepatotoxic mycotoxin with estrogenic and anabolic activity found in cereal grains worldwide. ZEA affects hematological and immunological parameters in humans and rodents. The compound
Yuquan Xu et al.
Applied and environmental microbiology, 79(6), 2038-2047 (2013-01-22)
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin with heat shock response and immune-modulatory activities. It features a dihydroxyphenylacetic acid lactone polyketide framework with structural similarities to resorcylic acid lactones like radicicol or zearalenone. A genomic locus was identified from the dehydrocurvularin
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