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Merck
CN

48505

Carbon tetrachloride

analytical standard

Synonym(s):

Tetrachloromethane

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About This Item

Empirical Formula (Hill Notation):
CCl4
CAS Number:
56-23-5
Molecular Weight:
153.82
EC Number:
200-262-8
UNSPSC Code:
12352200
PubChem Substance ID:
24872015
Beilstein/REAXYS Number:
1098295
MDL number:
MFCD00000785

Key Documents

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InChI key

VZGDMQKNWNREIO-UHFFFAOYSA-N

InChI

1S/CCl4/c2-1(3,4)5

SMILES string

ClC(Cl)(Cl)Cl

grade

analytical standard

vapor density

5.32 (vs air)

vapor pressure

143 mmHg ( 30 °C), 91 mmHg ( 20 °C)

packaging

ampule of 1000 mg

availability

not available in Japan

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

−23 °C (lit.)

density

1.594 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation

target_organs

Liver,Kidney

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
LB91921V
LB81636V
LB77812
LB74832
LB72472

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Lutz W D Weber et al.
Critical reviews in toxicology, 33(2), 105-136 (2003-04-24)
The use of many halogenated alkanes such as carbon tetrachloride (CCl4), chloroform (CHCl3) or iodoform (CHI3), has been banned or severely restricted because of their distinct toxicity. Yet CCl4 continues to provide an important service today as a model substance
Samuele De Minicis et al.
Hepatology (Baltimore, Md.), 59(5), 1738-1749 (2013-08-21)
Nonalcoholic fatty liver disease (NAFLD) may lead to hepatic fibrosis. Dietary habits affect gut microbiota composition, whereas endotoxins produced by Gram-negative bacteria stimulate hepatic fibrogenesis. However, the mechanisms of action and the potential effect of microbiota in the liver are
Carbon tetrachloride: genetic effects and other modes of action.
D McGregor et al.
Mutation research, 366(3), 181-195 (1996-12-01)
Samar Basu
Toxicology, 189(1-2), 113-127 (2003-06-25)
Hepatic injury through carbon tetrachloride (CCl(4)) induced lipid peroxidation is well known and has been extensively used in the experimental models to understand the cellular mechanisms behind oxidative damage and further to evaluate the therapeutic potential of drugs and dietary
Bi-Sen Ding et al.
Nature, 505(7481), 97-102 (2013-11-22)
Chemical or traumatic damage to the liver is frequently associated with aberrant healing (fibrosis) that overrides liver regeneration. The mechanism by which hepatic niche cells differentially modulate regeneration and fibrosis during liver repair remains to be defined. Hepatic vascular niche
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