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Merck
CN

48552

N-Nitrosodimethylamine

analytical standard

Synonym(s):

Dimethylnitrosamine

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About This Item

Linear Formula:
(CH3)2NNO
CAS Number:
62-75-9
Molecular Weight:
74.08
UNSPSC Code:
41121813
PubChem Substance ID:
24872088
EC Number:
200-549-8
MDL number:
MFCD00002053

Key Documents

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InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

SMILES string

CN(C)N=O

grade

analytical standard

agency

EPA TO-7

vapor pressure

5 mmHg ( 20 °C)

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 100 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.437 (lit.)

bp

153 °C/774 mmHg (lit.)

density

1.01 g/mL (lit.)

application(s)

environmental

format

neat

storage temp.

2-8°C

General description

N-Nitrosodimethylamine is a potent carcinogen, which can be formed in conditions of wastewater disinfection process, via the reaction between monochloramine and organic nitrogen-containing precursors.

Application

N-Nitrosodimethylamine may be used as an analytical reference standard for the quantification of the analyte in aqueous samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Induces gastric, liver, kidney and lung cancer in mice and rats.

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 2 - Carc. 1B - STOT RE 1

target_organs

Liver

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

141.8 °F - closed cup

flash_point_c

61.0 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Lot/Batch Number
LC25707V
LC22798V
LC17701V
LC14356V
LC09664V

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Characterization and fate of N-nitrosodimethylamine precursors in municipal wastewater treatment plants
Mitch.AW and Sedlak.LD
Environmental Science & Technology, 38, 1445-1454 (2004)
Determination of N-Nitrosamines by Gas Chromatography Coupled to Quadrupole?Time-of-Flight Mass Spectrometry in Water Samples
Sieira JB, et al.
Separations, 7(1) (2020)
N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC?MS/MS
Plumlee HM, et al.
Water Research, 42(1-2), 347-355 (2008)
High-performance liquid chromatography with fluorescence detection for aqueous analysis of nanogram-level N-nitrosodimethylamine
Cha W, et al.
Analytica Chimica Acta, 566(1), 109-116 (2006)
Ming-Fen Lee et al.
Food & function, 4(3), 470-475 (2013-01-08)
Curcumin has been extensively studied for its therapeutic effects in a variety of disorders. Fermented soy consumption is associated with a low incidence rate of chronic diseases in many Asian countries. The aim of this study was to investigate the
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