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Merck
CN

48670

N-Nitrosodimethylamine (NDMA) solution

certified reference material, 200 μg/mL in methanol

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About This Item

CAS Number:
62-75-9
UNSPSC Code:
12352200
MDL number:
MFCD00002053
NACRES:
NA.24

Key Documents

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Product Name

N-Nitrosodimethylamine (NDMA) solution, certified reference material, 200 μg/mL in methanol

SMILES string

N(N=O)(C)C

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

grade

certified reference material
TraceCERT®

agency

EPA TO-7

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

concentration

200 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-30°C

Quality Level

300

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Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Application

N-Nitrosodimethylamine (NDMA) solution may be used as an analytical reference standard for the determination of nitrosamines in water liquid chromatography coupled to tandem mass spectrometry.

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodimethylamine (NDMA) solution is commonly employed as a certified reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with  ISO 17034  and  ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of eight nitrosamines in water at the ng L- 1 levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry
Ripolles, et al.
Analytica Chimica Acta, 702, 62-71 (2011)
Lactic acid bacteria directly degrade N-nitrosodimethylamine and increase the nitrite-scavenging ability in kimchi
Kim H-S, et al.
Food Control, 71, 101-109 (2017)
The role of Cu (II) in the reduction of N-nitrosodimethylamine with iron and zinc
Han Y, et al.
Chemosphere, 167, 171-177 (2017)
Man-Chun Huang et al.
Food chemistry, 138(1), 227-233 (2012-12-26)
A sensitive procedure, microwave-assisted extraction (MAE) coupled dispersive micro solid-phase extraction (D-μ-SPE), was developed to extract N-nitrosodimethylamine (NDMA) and other six volatile N-nitrosamines (NAms) from meat products. Parameters affecting the efficiency of MAE and D-μ-SPE were systematically investigated. For MAE
Maria José Farré et al.
Environmental science & technology, 46(23), 12904-12912 (2012-11-09)
UV-C radiation is the U.S. EPA recommended technology to remove N-nitrosodimethylamine (NDMA) during drinking and recycled water production. Frequently, H(2)O(2) is added to the treatment to remove other recalcitrant compounds and to prevent NDMA reformation. However, the transformation of NDMA
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