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Merck
CN

48670

Supelco

N-Nitrosodimethylamine (NDMA) solution

certified reference material, 200 μg/mL in methanol

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About This Item

CAS Number:
62-75-9
MDL number:
MFCD00002053
UNSPSC Code:
12352200

Key Documents

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grade

certified reference material
TraceCERT®

Quality Level

300

Agency

EPA TO-7

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

concentration

200 μg/mL in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-30°C

SMILES string

N(N=O)(C)C

InChI

1S/C2H6N2O/c1-4(2)3-5/h1-2H3

InChI key

UMFJAHHVKNCGLG-UHFFFAOYSA-N

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General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.
N-Nitrosodimethylamine (NDMA) solution is commonly employed as a certified reference compound in analytical chemistry. It is utilized in chromatographic and spectrometric techniques for the detection and quantification of nitrosamines in chemical, pharmaceutical, and environmental matrices.

Application

N-Nitrosodimethylamine (NDMA) solution may be used as an analytical reference standard for the determination of nitrosamines in water liquid chromatography coupled to tandem mass spectrometry.

Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with  ISO 17034  and  ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The role of Cu (II) in the reduction of N-nitrosodimethylamine with iron and zinc
Han Y, et al.
Chemosphere, 167, 171-177 (2017)
Determination of eight nitrosamines in water at the ng L- 1 levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry
Ripolles, et al.
Analytica Chimica Acta, 702, 62-71 (2011)
Lactic acid bacteria directly degrade N-nitrosodimethylamine and increase the nitrite-scavenging ability in kimchi
Kim H-S, et al.
Food Control, 71, 101-109 (2017)
Jin Woong Kim et al.
Journal of magnetic resonance imaging : JMRI, 53(2), 554-563 (2020-07-03)
Liver fibrosis is characterized by the excessive accumulation of extracellular matrix proteins. Electrical conductivity imaging at low frequency can provide novel contrast because the contrast mechanisms originate from the changes in the concentration and mobility of ions in the extracellular
Ina Kristiana et al.
Water research, 47(2), 535-546 (2012-11-21)
N-Nitrosamines are a class of disinfection by-products (DBPs) that have been reported to be more toxic than the most commonly detected and regulated DBPs. Only a few studies investigating the formation of N-nitrosamines from disinfection of natural waters have been
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