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Merck
CN

49054

Methoxychlor

PESTANAL®, analytical standard

Synonym(s):

1,1,1-Trichloro-2,2-bis-(p-methoxyphenyl)ethane, 2,2-Bis(4-methoxyphenyl)-1,1,1-trichloroethane, DMDT

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About This Item

Empirical Formula (Hill Notation):
C16H15Cl3O2
CAS Number:
Molecular Weight:
345.65
EC Number:
200-779-9
UNSPSC Code:
41121813
PubChem Substance ID:
Beilstein/REAXYS Number:
2057367
MDL number:
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InChI key

IAKOZHOLGAGEJT-UHFFFAOYSA-N

InChI

1S/C16H15Cl3O2/c1-20-13-7-3-11(4-8-13)15(16(17,18)19)12-5-9-14(21-2)10-6-12/h3-10,15H,1-2H3

SMILES string

COc1ccc(cc1)C(c2ccc(OC)cc2)C(Cl)(Cl)Cl

grade

analytical standard

product line

PESTANAL®

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

86-88 °C (lit.)

application(s)

agriculture
environmental

format

neat

storage temp.

room temp

Quality Level

Gene Information

mouse ... Esr1(13982)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Pesticide with estrogenic activity.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

农药列管产品
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Andrea C Gore et al.
Molecular endocrinology (Baltimore, Md.), 25(12), 2157-2168 (2011-10-22)
Gestational exposure to the estrogenic endocrine disruptor methoxychlor (MXC) disrupts the female reproductive system at the molecular, physiological, and behavioral levels in adulthood. The current study addressed whether perinatal exposure to endocrine disruptors re-programs expression of a suite of genes
M D Reuber
Environmental health perspectives, 36, 205-219 (1980-06-01)
Methoxychlor is carcinogenic for the liver of C3H and BALB/c mice and Osborne-Mendel rats, and possibly for the liver of dogs. Methoxychlor is also carcinogenic for the testis of BALB/c male mice, bone of B6C3F1 female mice, and the ovary
P Palanza et al.
Neurotoxicology and teratology, 24(1), 55-69 (2002-02-12)
There has been increasing interest, both at the scientific and regulatory level, in the use of ethological methods for evaluating neural effects of endocrine disrupters. We present a series of ethological studies on the effects of maternal exposure to low
V K Gupta et al.
Water research, 45(13), 4047-4055 (2011-06-15)
Waste rubber tire has been used for the removal of pesticides from waste water by adsorption phenomenon. By applying successive chemical and thermal treatment, a basically cabonaceous adsorbent is prepared which has not only a higher mesopore, macropore content but
Hye-Rim Lee et al.
International journal of molecular medicine, 29(5), 883-890 (2012-02-07)
Various endocrine disrupting chemicals (EDCs) are exogenous compounds found in the environment and have the potential to interfere with the endocrine system and hormonal regulation. Among EDCs, bisphenol A (BPA) and 1,1,1-trichloro-2,2-bis(4-methoxyphenol)-ethane [methoxychlor (MXC)] have estrogenic activity resulting in a variety

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