57943
SUPELCOSIL™ LC-18-DB (3 µm) HPLC Columns
L × I.D. 25 cm × 2.1 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
Product Name
SUPELCOSIL™ LC-18-DB HPLC Column, 3 μm particle size, L × I.D. 25 cm × 2.1 mm
Agency
suitable for USP L1
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
extent of labeling
11.0% Carbon loading
parameter
0-70 °C temperature
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 2.1 mm
surface area
170 m2/g
surface coverage
surface coverage 3.1 μmol/m2
matrix
silica gel, spherical particle platform
matrix active group
C18 (octadecyl) phase
particle size
3 μm
pore size
120 Å
application(s)
food and beverages
compatibility
for use with PTH-AA
separation technique
reversed phase
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General description
SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Regulatory Information
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P K Kunicki
Journal of chromatography. B, Biomedical sciences and applications, 755(1-2), 331-335 (2001-06-08)
A HPLC-UV determination of loratadine in human plasma is presented. After simple liquid-liquid extraction with 2-methylbutane-hexane (2:1) and evaporation of organic phase the compounds were re-dissolved in 0.01 M HCl, evaporated again and finally separated on a Supelcosil LC-18-DB column.
S L Bramer et al.
Journal of pharmaceutical and biomedical analysis, 26(4), 637-650 (2001-08-23)
An LC/MS/MS method for the simultaneous determination of cilostazol, a quinolinone derivative, and three active metabolites, OPC-13015, OPC-13213, and OPC-13217, in human plasma was developed and validated. Cilostazol, its metabolites, and the internal standard, OPC-3930 were extracted from human plasma
M Carini et al.
Journal of pharmaceutical and biomedical analysis, 18(1-2), 201-211 (1998-12-24)
A study was undertaken for the characterization and quantitative determination of the main urinary metabolites of the non-steroidal anti-inflammatory drug (NSAID) nimesulide (4-nitro-2-phenoxy-methanesulfonanilide) in man following single oral administration (200 mg). Urines were collected from six healthy volunteers at 12
D C Holland et al.
Journal of AOAC International, 78(4), 1067-1071 (1995-07-01)
A liquid chromatographic (LC) method is described for the simultaneous determination of the triazine herbicides, simazine (SIM), atrazine (ATZ), and propazine (PRO) in the 12.5-100 ppb range in catfish. The herbicides are extracted from catfish homogenates with ethyl acetate, followed
Xinghua Sun et al.
Anticancer research, 25(1A), 59-62 (2005-04-09)
A rapid, sensitive and specific high-performance liquid chromatographic (HPLC) method for the separation and quantification of L-methionine in plasma has been developed. After derivatization of plasma amino acids with o-phthalaldehyde (OPA), a 50 microl sample was loaded on a reversed-phase
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