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Merck
CN

72942

Saxitoxin-15N7 dihydrochloride solution

10 μg/g in hydrochloric acid (nominal concentration), analytical standard

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About This Item

Empirical Formula (Hill Notation):
C10H1715N7O4 · 2HCl
Molecular Weight:
379.16
NACRES:
NA.21
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SMILES string

[H][C@@]12[C@]3([15NH]C([15NH]2)=[15NH])[15N](CCC3(O)O)C([15NH][C@H]1COC([15NH2])=O)=[15NH]

grade

analytical standard

concentration

10 μg/g in hydrochloric acid (nominal concentration)

technique(s)

HPLC: suitable, LC/MS: suitable, liquid chromatography (LC): suitable, mass spectrometry (MS): suitable

application(s)

food and beverages

format

single component solution

storage temp.

−20°C

Quality Level

General description

This is the 15N isotope-labelled analog of saxitoxin. Saxitoxin is a highly potent neurotoxin in the paralytic shellfish toxin (PST) family, produced by marine dinoflagellates and some freshwater cyanobacteria, that can accumulate in bivalves and cause paralytic shellfish poisoning in humans. Testing is critical for seafood safety and regulatory compliance, and modern monitoring programs increasingly rely on LC–MS/MS and related chemistry-based methods to quantify saxitoxin and its many analogues in shellfish and water. A stable isotope–labeled internal standard enables isotope dilution mass spectrometry (IDMS), which corrects for matrix effects and recovery losses, yielding high‑accuracy, low‑uncertainty results. Because the labeled standard co-elutes and ionizes like the native toxin, quantification based on isotope ratios improves method robustness and inter-laboratory comparability.


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Analysis Note

10 μg/g in 66.3 µmol/l HCl in water

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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