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BP1257

Rivastigmine hydrogen tartrate

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Rivastigmine tartrate, ENA-713, Ethylmethyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester, N-Ethyl-N-methyl-carbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester tartrate, S-Rivastigmine tartrate

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About This Item

Empirical Formula (Hill Notation):
C14H22N2O2 · C4H6O6
CAS Number:
129101-54-8
Molecular Weight:
400.42
MDL number:
MFCD09955042
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

rivastigmine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

N([C@@H](C)c1cc(ccc1)OC(=O)N(CC)C)(C)C.O[C@@H]([C@H](O)C(=O)O)C(=O)O

InChI

1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m00/s1

InChI key

GWHQHAUAXRMMOT-RWALOXMOSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Rivastigmine hydrogen tartrate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Rivastigmine Transdermal Patches
  • Rivastigmine Capsules
  • Rivastigmine Oral Solution

    • Biochem/physiol Actions

    Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor that enhances cognitive function in patients with Alzheimer′s and Parkinson′s diseases. Rivastigmine inhibits both butyrylcholinesterase and acetylcholinesterase.
    Rivastigmine is an orally available, brain penetrant, reversible cholinesterase inhibitor.

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

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    pictograms

    Skull and crossbonesEnvironment
    GHS06,GHS09

    signalword

    Danger

    hcodes

    H300,H411

    Hazard Classifications

    Acute Tox. 2 Oral - Aquatic Chronic 2

    Storage Class

    6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Regulatory Information

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    Global Trade Item Number

    SKUGTIN
    BP125704065269082217