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Merck
CN

Hydrogen chloride solution

0.5 N in methanol

Synonym(s):

Methanolic HCl, Hydrochloric acid solution

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About This Item

Empirical Formula (Hill Notation):
HCl
CAS Number:
Molecular Weight:
36.46
UNSPSC Code:
12352301
Grade:
derivatization grade ((GC derivatization))
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Product Name

Methanolic HCl, 0.5 N

grade

derivatization grade ((GC derivatization))

form

liquid

reaction suitability

reagent type: derivatization reagent
reaction type: Esterifications

packaging

pkg of 10 × 5 mL (33095)

concentration

0.5 N

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

General description

Methanolic HCl (hydrochloric acid in methanol) is particularly useful for preparing methyl esters of volatile (short chain) fatty acids. Fatty acids are esterified by heating them with an anhydrous alcohol (e.g., methanol) in the presence of an acidic catalyst (e.g., HCl) in a sealed vessel at a high temperature for a short time. In the reaction, a fatty acid molecule and an alcohol molecule are joined, with the release of a water molecule. The derivatives can be quickly and easily recovered, quantitatively, from the reaction medium.

Application

Suitable for derivatization of fatty acids, lipids and formic and acetic acid (in cigarett smoke).

Features and Benefits

  • Derivatization of fatty acids, particularly volatile (short chain) fatty acids.

  • Clean reaction (no side reaction) with volatile by-products.

  • Provides clean, fast, quantitative derivatization.

Other Notes

Reagent for methyl esters.


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