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MET677A

Leptophos oxon

analytical standard

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About This Item

CAS Number:
25006-32-0
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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Product Name

Leptophos oxon, analytical standard

InChI

1S/C13H10BrCl2O3P/c1-18-20(17,9-5-3-2-4-6-9)19-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3

InChI key

MAKUYRKZFGSMMG-UHFFFAOYSA-N

grade

analytical standard

packaging

ampule of 50 mg

manufacturer/tradename

Chem Service, Inc. MET-677A

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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J H Reinders et al.
Toxicology letters, 17(1-2), 107-111 (1983-06-01)
In comparing neurotoxic esterase (NTE) inhibition properties of a series of phenylphosphonates, it was discovered that certain compounds including leptophos inhibited mipafox-insensitive phenylvalerate hydrolases. This leads to erroneous values for NTE inhibition which can be corrected by a differential assay:
S A Soliman et al.
Journal of analytical toxicology, 5(4), 183-186 (1981-07-01)
Hen brain microsomal preparation has phenyl valerate-hydrolyzing activity associated with neurotoxic esterase activity. Part of that activity is due to paraoxon-insensitive esterases and a sub-part of this is sensitive to neurotoxic organophosphates, i.e., mipafox and leptophosoxon. This neurotoxic agent sensitive
S H Preissig et al.
Environmental research, 17(2), 242-250 (1978-10-01)
Recent investigation into a possible association between exposure to Leptophos and neurological symptoms in insecticide factory workers makes study of the neurological effects of Leptophos in the experimental situation particularly important. The present study utilizes a single oral dose of
M H Fulton et al.
Toxicology letters, 26(2-3), 175-180 (1985-08-01)
The toxic and teratogenic effects of 4 organophosphorus compounds (phenyl saliginen cyclic phosphate (PSCP), leptophos-oxon (LPTO), tri-o-tolyl phosphate (TOTP), and paraoxon (PXN] were investigated in the embryos of 3 species of frogs. Developmental abnormalities were observed in surviving embryos of
A H El-Sebae et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 16(4), 465-474 (1981-01-01)
Five organophosphorous insecticides: Leptophos, EPN, Cyanofenphos, trichloronate and salithion proved to cause irreversible ataxia not only to chicken but also to mice and sheep. TOCP was included as a reference. Cyanofenphos blocked the catecholamine B-receptor binding activity with 3H-norepinephrine at

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