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Merck
CN

MET678B

3-Methyl-4-nitrophenol

analytical standard

Synonym(s):

4-Nitro-m-cresol, 5-Hydroxy-2-nitrotoluene

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About This Item

Linear Formula:
CH3C6H3(NO2)OH
CAS Number:
Molecular Weight:
153.14
EC Number:
219-952-5
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
1868105
MDL number:
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InChI key

PIIZYNQECPTVEO-UHFFFAOYSA-N

InChI

1S/C7H7NO3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3

SMILES string

Cc1cc(O)ccc1[N+]([O-])=O

grade

analytical standard

packaging

ampule of 1000 mg

manufacturer/tradename

Chem Service, Inc. MET-678B

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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ChunMei Li et al.
European journal of pharmacology, 543(1-3), 194-199 (2006-07-11)
In our continuing studies on nitrophenol derivatives as vasodilators in diesel exhaust particles, we have reported that nitrophenols in diesel exhaust particles possess not only vasodilatory activity but also estrogenic activity in vitro and in vivo, as well as anti-androgenic
Chunmei Li et al.
Biological & pharmaceutical bulletin, 30(12), 2376-2380 (2007-12-07)
In previous studies, we found that 3-methyl-4-nitrophenol (4-nitro-m-cresol; PNMC) isolated from diesel exhaust particles, and also a degradation product of the insecticide fenitrothion, exhibited testicular toxicity in the male of both immature rat and adult Japanese quail. It is well
Zhuo Yue et al.
Environmental toxicology, 27(11), 653-661 (2011-03-05)
The 3-methyl-4-nitrophenol (4-nitro-m-cresol; PNMC) exists in diesel exhaust particles (DEP), and is also one of the degradation products of insecticide fenitrothion. To assess potential nephrotoxicity of PNMC, male Sprague-Dawley (SD) rats were subcutaneously dosed with PNMC at 1, 10, and
Qing Li et al.
Human & experimental toxicology, 30(7), 665-674 (2010-07-14)
Fenitrothion (FNT) is used throughout the world as an insecticide in agriculture. To investigate the effect of FNT on the splenocytes and the underlying mechanism, FNT and its main metabolite, 3-methyl-4-nitrophenol (MNP), were administered orally to Wistar rats in daily
ChunMei Li et al.
Biological & pharmaceutical bulletin, 31(11), 2158-2161 (2008-11-05)
We previously showed that 3-methyl-4-nitrophenol (4-nitro-m-cresol, PNMC), a component of diesel exhaust particles and a degradation product of the insecticide fenitrothion, has reproductive toxicity in adult male and immature female Japanese quail (Coturnix japonica). Here we investigated effects of PNMC

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