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Merck
CN

N11969

Fenvalerate

analytical standard

Synonym(s):

α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)­iso­valerate

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About This Item

Empirical Formula (Hill Notation):
C25H22ClNO3
CAS Number:
51630-58-1
Molecular Weight:
419.90
Beilstein:
2025982
EC Number:
257-326-3
MDL number:
MFCD00055324
UNSPSC Code:
41116107

Key Documents

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grade

analytical standard

packaging

ampule of 250 mg

manufacturer/tradename

Chem Service, Inc. PS-1032

SMILES string

CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3

InChI

1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3

InChI key

NYPJDWWKZLNGGM-UHFFFAOYSA-N

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Biochem/physiol Actions

Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335,H410

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Fang B Yu et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(3), 198-207 (2013-01-30)
A fenvalerate-degrading bacterial strain F-7 was isolated from long-term contaminated sludge. Based on morphological, physiological and biochemical characterization, and phylogenetic analysis of 16S rRNA gene sequence, strain F-7 was identified as Sphingomonas sp. The bacterium could utilize fenvalerate as the
Xiaohua Gao et al.
American journal of physiology. Endocrinology and metabolism, 303(8), E1025-E1035 (2012-08-02)
Previously, we reported that fenvalerate (Fen) promotes proliferation of human uterine leiomyoma (UtLM) cells by enhancing progression of cells from G(0)-G(1) to S phase through molecular mechanisms independent of estrogen receptor-α and -β. The cyclin-dependent kinase (CDK) inhibitor p27, which
Jian-Hua Qu et al.
Toxicology, 292(2-3), 151-155 (2012-01-03)
Exposure to fenvalerate has been shown to be associated with decreased steroid hormone production by mouse Leydig tumor cells (MLTC-1) in our previous study and the interference with cAMP-PKA pathway cannot explain this inhibitory effect completely. In this study, the
Nathalie C Stampfli et al.
Aquatic toxicology (Amsterdam, Netherlands), 127, 9-20 (2012-10-16)
Climate change models predict an increase in the frequency and intensity of extreme fluctuations in water level in aquatic habitats. Therefore, it is necessary to understand the combined effects of hydrological fluctuations and toxicants on aquatic biological communities. We investigated
Lisbeth Schnug et al.
Environmental toxicology and chemistry, 32(4), 937-947 (2013-02-02)
The aim of the present study was to determine the toxicity of a mixture containing the biocides picoxystrobin, esfenvalerate, and triclosan to the reproduction and adult survival of two consecutive generations of Eisenia fetida (Savigny, 1826). Concentration addition and independent
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