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N12249

Isofenphos

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C15H24NO4PS
CAS Number:
25311-71-1
Molecular Weight:
345.39
PubChem Substance ID:
329818526
UNSPSC Code:
41116107
Beilstein/REAXYS Number:
2949615
MDL number:
MFCD00041805

Key Documents

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SMILES string

CCOP(=S)(NC(C)C)Oc1ccccc1C(=O)OC(C)C

InChI key

HOQADATXFBOEGG-UHFFFAOYSA-N

InChI

1S/C15H24NO4PS/c1-6-18-21(22,16-11(2)3)20-14-10-8-7-9-13(14)15(17)19-12(4)5/h7-12H,6H2,1-5H3,(H,16,22)

grade

analytical standard

form

liquid

packaging

ampule of 100 mg

manufacturer/tradename

Chem Service, Inc. PS-1003

General description

Isofenphos is an organophosphorus pesticide, used for the control of larvae of Popillia japonica Newman, soil-dwelling pests of corn (Amaze), Delia antiqua (Onion flies), Chamaepsila rosae (carrot flies), wireworms, etc. Toxicologically, the pesticide acts by the inhibition of acetylcholinesterase activity.

Application

Isofenphos may be used as an analytical reference standard for the determination of the pesticide residue in meat samples, leeks, rice and human tissues by various chromatography techniques.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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A Garrido-Frenich et al.
Journal of chromatography. A, 1133(1-2), 315-321 (2006-09-05)
The assessment of the recovery factor with the analyte concentration in meat samples has been studied for the determination of organochlorine and organophosphorus pesticides in meat by gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS). For that purpose, recent IUPAC recommendations, which
Dong Woon Lee et al.
Journal of economic entomology, 95(5), 918-926 (2002-10-31)
The oriental beetle Exomala (Anomala) orientalis (Waterhouse) is an important pest of turfgrass in Korean golf courses, and although a few chemical insecticides are registered for insect pest control, they are not very effective against scarab larvae. There is also
Rapid determination of organophosphorous pesticides in leeks by gas chromatography-triple quadrupole mass spectrometry
Qu LJ, et al.
Food Chemistry, 122(1), 327-332 (2010)
R C Wester et al.
Fundamental and applied toxicology : official journal of the Society of Toxicology, 19(4), 521-526 (1992-11-01)
Studies were done to determine the percutaneous absorption of isofenphos in human volunteers from whom informed consent had been obtained. In vivo absorption in man was 3.6 +/- 3.6% of applied dose for 24-hr exposure and 3.6 +/- 0.5% for
Angelo Moretto et al.
Archives of toxicology, 76(5-6), 367-375 (2002-07-11)
Species differences have been observed between hen and human clinical manifestations of isofenphos toxicities. Hens treated with the insecticide isofenphos (90 mg/kg p.o.) developed severe cholinergic toxicity followed by mild organophosphate-induced delayed polyneuropathy (OPIDP). However, a patient developed severe OPIDP
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