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Merck
CN

N12707

2,4′-DDE

analytical standard

Synonym(s):

2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethene, o,p′-DDE

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About This Item

Empirical Formula (Hill Notation):
C14H8Cl4
CAS Number:
Molecular Weight:
318.03
EC Number:
UNSPSC Code:
41116107
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grade

analytical standard

packaging

ampule of 50 mg

manufacturer/tradename

Chem Service, Inc. N-12707-50MG

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

format

neat

InChI

1S/C14H8Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8H

InChI key

ZDYJWDIWLRZXDB-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Certificates of Analysis (COA)

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R Benecke et al.
European journal of clinical pharmacology, 41(3), 259-261 (1991-01-01)
Mitotane (o,p'-DDD) can be used for the treatment of various adrenocortical diseases such as Cushing's syndrome, but the usual doses of 6-8 g per day are often associated with severe adverse effects. This paper reports the results of much lower
P Balaguer et al.
The Science of the total environment, 233(1-3), 47-56 (1999-09-24)
In order to characterize the estrogenic activity of chemicals, we established complementary in vitro recombinant receptor-reporter gene assays in stably transfected MCF-7 and HeLa cells. MCF-7 cells which express the endogenous estrogen receptor alpha (ER alpha) were stably transfected with
Diana M Papoulias et al.
Environmental health perspectives, 111(1), 29-32 (2003-01-08)
Despite being banned in many countries, dichlorodiphenyltrichloroethane (DDT) and its metabolites dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane (DDD) continue to be found in fish tissues at concentrations of concern. Like o,p -DDT, o,p -DDE is estrogenic and is believed to exert its
W Foster et al.
The Journal of clinical endocrinology and metabolism, 85(8), 2954-2957 (2000-08-18)
Man-made chemicals that have been shown to modulate endocrine function in animal models, so-called "endocrine disrupters", are suspected to play a role in the development of male reproductive tract abnormalities and neurobehaviroal deficits in children. However in utero exposure to
Anna A Kasperlik-Zaluska et al.
Journal of experimental therapeutics & oncology, 5(2), 125-132 (2006-02-14)
Our study aimed at evaluation of the relations between the plasma levels of mitotane (o,p'-DDD) and its metabolites, o,p'-DDA and o,p'-DDE, and the efficacy of Mitotane therapy during a long-term follow-up. Eighteen patients, aged 11 to 70 years, were included

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