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Merck
CN

PS676

Methamidophos

analytical standard

Synonym(s):

O,S-Dimethyl phosphoramidothioate

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About This Item

Empirical Formula (Hill Notation):
C2H8NO2PS
CAS Number:
Molecular Weight:
141.13
EC Number:
233-606-0
UNSPSC Code:
41116107
PubChem Substance ID:
Beilstein/REAXYS Number:
8137714
MDL number:
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InChI key

NNKVPIKMPCQWCG-UHFFFAOYSA-N

InChI

1S/C2H8NO2PS/c1-5-6(3,4)7-2/h1-2H3,(H2,3,4)

SMILES string

COP(N)(=O)SC

grade

analytical standard

packaging

ampule of 100 mg

manufacturer/tradename

Chem Service, Inc. PS-676

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

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General description

Methamidophos is a nonselective type of organophosphorus insecticide and a potent acetylcholinesterase inhibitor, which is commonly used in controlling a broad spectrum of pest insects such as chewing and sucking insects and spider mites on citrus fruits, ornamental plants, stone fruits and other intensive agricultural crops.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

413.6 °F - closed cup

flash_point_c

212 °C - closed cup

Regulatory Information

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Certificates of Analysis (COA)

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Titanium dioxide mediated photocatalytic degradation of methamidophos in aqueous phase.
Wei L, et al.
Journal of Hazardous Materials, 164(1), 154-160 (2009)
Zhong-Lan Shen et al.
Bioscience, biotechnology, and biochemistry, 75(3), 473-479 (2011-03-11)
An analytical methodology for the analysis of methamidophos in water and soil samples incorporating a molecularly imprinted solid-phase extraction process using methamidophos-imprinted polymer was developed. Binding study demonstrated that the polymer exhibited excellent affinity and high selectivity to the methamidophos.
Guilherme L Emerick et al.
Environmental toxicology and chemistry, 31(2), 239-245 (2011-11-03)
Many chiral pesticides are introduced into the environment as racemates, although their pesticidal activity is usually the result of preferential reactivity of only one enantiomer, while the other enantiomer may have toxic effects against nontarget organisms. Methamidophos (O,S-dimethyl phosphoramidothioate), a
Hongkun Li et al.
Talanta, 87, 93-99 (2011-11-22)
With citrate-coated Au nanoparticles as colorimetric probe, a novel visual method for rapid assay of organophosphorus pesticides has been developed. The assay principle is based on catalytic hydrolysis of acetylthiocholine into thiocholine by acetylcholinesterase, which induces the aggregation of Au
Guilherme L Emerick et al.
Toxicology, 292(2-3), 145-150 (2011-12-27)
The current Organisation for Economic Co-operation and Development (OECD) guidelines for evaluating organophosphorus-induced delayed neuropathy (OPIDN) require the observation of dosed animals over several days and the sacrifice of 48 hens. Adhering to these protocols in tests with enantiomers is

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