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USP

Bupivacaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
Bupivacaine hydrochloride monohydrate, 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride hydrate
Empirical Formula (Hill Notation):
C18H28N2O · HCl · H2O
CAS Number:
Molecular Weight:
342.90
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

bupivacaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bupivacaine hydrochloride USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solutions for assay by using liquid chromatography in conjunction with a UV detector according to the given below monographs of United States Pharmacopeia (USP):
  • Fentanyl Citrate and Bupivacaine Hydrochloride Compounded Injection
  • Bupivacaine Hydrochloride Injection
  • Bupivacaine Hydrochloride and Epinephrine Injection
  • Bupivacaine Hydrochloride

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Bupivacaine Hydrochloride Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(3), 611-611 (2023)
Bupivacaine Hydrochloride and Epinephrine Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 612-612 (2018)
Bupivacaine Hydrochloride
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 41(3), 610-610 (2020)
Fentanyl Citrate and Bupivacaine Hydrochloride Compounded Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(1), 1850-1850 (2020)
I Demirel et al.
European review for medical and pharmacological sciences, 18(7), 1067-1072 (2014-04-26)
Just as hip prosthesis, most of the patients undergoing orthopedic lower extremity surgery (OLES) belong to the advanced age group. Sciatic nerve block combined with psoas compartment block is used as a technique alternative to central neuraxial block and GA.

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