SMILES string
[S](=O)(=O)(O)O.N1CCC(N=C1N)C2NC(=O)\C(=C\NC(=O)N)\NC(=O)C(NC(=O)C(NC(=O)C(CNC2=O)N)CO)CNC(=O)CC(N)CCCN
InChI
1S/C25H44N14O8.H2O4S/c26-4-1-2-11(27)6-17(41)32-8-14-20(43)35-15(9-34-25(30)47)21(44)39-18(13-3-5-31-24(29)38-13)23(46)33-7-12(28)19(42)37-16(10-40)22(45)36-14;1-5(2,3)4/h9,11-14,16,18,40H,1-8,10,26-28H2,(H,32,41)(H,33,46)(H,35,43)(H,36,45)(H,37,42)(H,39,44)(H3,29,31,38)(H3,30,34,47);(H2,1,2,3,4)/b15-9-;
InChI key
AJQVUIHGEOLMDY-SOCRLDLMSA-N
grade
pharmaceutical primary standard
API family
capreomycin
form
solid
manufacturer/tradename
USP
application(s)
USP Biologics
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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General description
Capreomycin sulfate is a cyclic polypeptide antibiotic produced by Streptomyces capreolus. It is used as a second-line treatment for multidrug-resistant tuberculosis (MDR-TB) and exhibits bacteriostatic activity by inhibiting protein synthesis through ribosomal binding. The USP reference standard supports microbiological assay methods and identity confirmation by chromatographic and spectroscopic techniques.
The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Application
- Capreomycin for Injection
- Capreomycin Sulfate
Analysis Note
Other Notes
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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