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1269232

USP

Famotidine Related Compound C

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanamide monohydrochloride, 3-{[2-(Diaminomethyleneamino)thiazol-4-yl]methylthio}-N-sulfamoylpropanamide hydrochloride
Empirical Formula (Hill Notation):
C8H14N6O3S3 · HCl
CAS Number:
Molecular Weight:
374.89
NACRES:
NA.24

biological source

synthetic

grade

pharmaceutical primary standard

Agency

USP

API family

famotidine

form

powder

packaging

pkg of 25 mg

manufacturer/tradename

USP

storage condition

protect from light

color

white to off-white

mp

298.4-314.6 °F (148—157°C)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C8H14N6O3S3.ClH/c9-7(10)13-8-12-5(4-19-8)3-18-2-1-6(15)14-20(11,16)17;/h4H,1-3H2,(H,14,15)(H2,11,16,17)(H4,9,10,12,13);1H

InChI key

LBBLJRHWJZWHQA-UHFFFAOYSA-N

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This Item
1269254PHR2912PHR2911
USP

USP

1269232

Famotidine Related Compound C

USP

USP

1269254

Famotidine Related Compound E

form

powder

form

powder

form

-

form

-

manufacturer/tradename

USP

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical

format

neat

format

neat

format

-

format

-

biological source

synthetic

biological source

synthetic

biological source

-

biological source

-

General description

Famotidine Related Compound C (Famotidine Impurity C) is an impurity of famotidine, which is a hydrophilic, cationic, histamine H2 receptor antagonist drug that effectively inhibits gastric acid secretion in humans.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Stability indicating method for famotidine in pharmaceuticals using porous graphitic carbon column
Helali N and Monser L
Journal of Separation Science, 31(2) (2008)
Famotidine
Pharmacopeia, US
United States Pharmacopeia, 39(1)(1-2), 1815-1815 (2020)
Capillary zone electrophoresis method for the determination of famotidine and related impurities in pharmaceuticals
Helali N, et al.
Talanta, 74(4) (2008)
RP-HPLC determination of famotidine and its potential impurities in pharmaceuticals
Helali N, et al.
Chromatographia, 60(7-8) (2004)
Potentiometric determination of famotidine in pharmaceutical formulations
Ayad MM, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(1-2) (2002)

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