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USP

Folic acid

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
PteGlu, Pteroyl-L-glutamic acid, Vitamin M
Empirical Formula (Hill Notation):
C19H19N7O6
CAS Number:
Molecular Weight:
441.40
Beilstein:
100781
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

folic acid

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

NC(N1)=NC(C2=C1N=CC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=O

InChI

1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

InChI key

OVBPIULPVIDEAO-LBPRGKRZSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Folic acid USP reference standard suitable for use in specified USP compendial quality tests and assays.

Also used to prepare standard, standard stock, system suitability stock and system suitability solution during the assay, identification, impurity analysis, and performance test by using liquid chromatography coupled with UV detector according to the given below monographs of United States Pharmacopeia (USP): 
  • Folic Acid Tablets
  • Folic Acid assay
  • Folic Acid Compounded Oral Solution
  • Folic Acid

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1


Certificates of Analysis (COA)

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Folic Acid assay
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 48(3), 6689-6689 (2022)
Folic Acid Tablets
United States Pharmacopeia, 48(3), 2028-2028 (2022)
Folic Acid
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 29(2), 2026-2026 (2020)
Folic Acid Compounded Oral Solution
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5), 2027-2027 (2017)
Zohra S Lassi et al.
The Cochrane database of systematic reviews, 3(3), CD006896-CD006896 (2013-04-02)
During pregnancy, fetal growth causes an increase in the total number of rapidly dividing cells, which leads to increased requirements for folate. Inadequate folate intake leads to a decrease in serum folate concentration, resulting in a decrease in erythrocyte folate

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