1500003
USP
Paromomycin sulfate
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
Paromomycin sulfate salt, Aminosidine sulfate
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About This Item
grade
pharmaceutical primary standard
API family
paromomycin
form
solid
manufacturer/tradename
USP
application(s)
USP Biologics
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
[S](=O)(=O)(O)O.N[C@H]1[C@H](O[C@H]([C@H]([C@@H]1O)O)CN)O[C@@H]2[C@H](OC([C@@H]2O)O[C@@H]3[C@H]([C@@H](C[C@@H](C3O[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O)CO)N)N)O)CO
InChI
1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18?,19-,20-,21-,22-,23?;/m1./s1
InChI key
LJRDOKAZOAKLDU-UMIPPVEZSA-N
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General description
Paromomycin sulfate is an aminoglycoside antibiotic primarily used in the treatment of parasitic infections and certain bacterial infections. It inhibits protein synthesis at the 30S ribosomal subunit. The USP reference standard is employed in potency and identity assays.
The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.
The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.
Application
Also, for use with USP monographs such as:
- Paromomycin Sulfate Capsules
- Paromomycin Oral Solution
Other Notes
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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