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Merck
CN

1699049

USP

Tropicamide Related Compound D

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Phenylacetic acid, α-Toluic acid, α-Tolylic acid, Benzeneacetic acid, PAA

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About This Item

Linear Formula:
C6H5CH2CO2H
CAS Number:
Molecular Weight:
136.15
Beilstein:
1099647
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
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grade

pharmaceutical primary standard

vapor density

~4 (vs air)

vapor pressure

1 mmHg ( 97 °C)

API family

tropicamide

form

crystalline

manufacturer/tradename

USP

bp

265 °C (lit.)

mp

76-78 °C (lit.)

density

1.081 g/mL at 25 °C (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)Cc1ccccc1

InChI

1S/C8H8O2/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H,9,10)

InChI key

WLJVXDMOQOGPHL-UHFFFAOYSA-N

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General description

Tropicamide Related Compound D is an impurity that may form during the synthesis of tropicamide-based biologic products. Its presence is closely monitored, and as a USP reference standard, its levels must remain within acceptable limits to ensure the purity and safety of the final product. This compound is particularly important for ensuring the quality of biologics used in ocular applications.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tropicamide Related Compound D USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Tropicamide

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

This product is part of USP Biologics Program.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pha
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

269.6 °F - closed cup

Flash Point(C)

132 °C - closed cup

Regulatory Information

易制毒化学品(2类)

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Certificates of Analysis (COA)

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