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Merck
CN

V000532

Sigma-Aldrich

Calcein

Synonym(s):

Bis[N,N−bis(carboxymethyl)aminomethyl]fluorescein, Fluorescein-bis(methyliminodiacetic acid), Fluorexon

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About This Item

Empirical Formula (Hill Notation):
C30H26N2O13
CAS Number:
154071-48-4
Molecular Weight:
622.53
Beilstein:
8181068
EC Number:
215-957-1

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SMILES string

OC(=O)CN(CC(O)=O)Cc1cc2c(Oc3cc(O)c(CN(CC(O)=O)CC(O)=O)cc3C24OC(=O)c5ccccc45)cc1O

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Mathias Ohlin et al.
Lab on a chip, 15(16), 3341-3349 (2015-07-15)
We study the temperature-independent impact on cell viability of relevant physical parameters during long-term, high-acoustic-pressure ultrasonic exposure in a microfluidic chip designed for ultrasonic-standing-wave trapping and aggregation of cells. We use a light-intensity method and 5 μm polymer beads for
Mark H M Vries et al.
Angiogenesis, 18(2), 163-171 (2014-12-11)
The mechanisms of monocyte recruitment to arteriogenic collaterals are largely unknown. We investigated the role of chemokine (C-X-C-motif) ligand 1 (CXCL1) and its cognate receptor, chemokine (C-X-C-motif) receptor 2 (CXCR2) in arteriogenesis. After femoral artery ligation in Sprague-Dawley rats, either
Rafael Atillo Espiritu et al.
Biochemistry, 53(20), 3287-3293 (2014-04-30)
Amphidinol 3 (AM3), a polyhydroxy-polyene metabolite from the dinoflagellate Amphidinium klebsii, possesses potent antifungal activity. Although AM3 permeabilizes phospholipid membranes only in the presence of sterol, the detailed molecular basis by which AM3 recognizes sterols in membranes remains unknown. Here
Hanna Artsi et al.
Endocrinology, 155(9), 3508-3515 (2014-06-21)
Estrogen deficiency leads to rapid bone loss and skeletal fragility. Sclerostin, encoded by the sost gene, and a product of the osteocyte, is a negative regulator of bone formation. Blocking sclerostin increases bone mass and strength in animals and humans.
Ruslan I Dmitriev et al.
Cellular and molecular life sciences : CMLS, 72(2), 367-381 (2014-07-10)
Cell-permeable phosphorescent probes enable the study of cell and tissue oxygenation, bioenergetics, metabolism, and pathological states such as stroke and hypoxia. A number of such probes have been described in recent years, the majority consisting of cationic small molecule and
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