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Merck
CN

V000702

Sigma-Aldrich

Benzoyl peroxide

72.0-80.0%

Synonym(s):

Dibenzoyl peroxide

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About This Item

Linear Formula:
(C6H5CO)2O2
CAS Number:
94-36-0
Molecular Weight:
242.23
Beilstein:
984320
MDL number:
MFCD00003071
PubChem Substance ID:
329828170

Key Documents

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grade

synthesis grade

Assay

72.0-80.0%

autoignition temp.

176 °F

mp

105 °C (lit.)

SMILES string

O=C(OOC(=O)c1ccccc1)c2ccccc2

InChI

1S/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H

InChI key

OMPJBNCRMGITSC-UHFFFAOYSA-N

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Application

Widely used initiator, curing agent, and cross-linking agent in polymerization processes.

Pictograms

Exclamation markEnvironment
GHS07,GHS09

Signal Word

Warning

Hazard Statements

H317,H319,H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1

Storage Class Code

4.1A - Other explosive hazardous materials

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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A L Kraus et al.
Regulatory toxicology and pharmacology : RTP, 21(1), 87-107 (1995-02-01)
Topical benzoyl peroxide has been used in the treatment of acne for over 30 years, with no reports of adverse effects that could be related to skin carcinogenesis. Two case-control epidemiological studies have found a lack of association between the
Tarek Fakhouri et al.
Journal of drugs in dermatology : JDD, 8(7), 657-661 (2009-07-11)
Antibiotic resistance of Propionibacterium acnes (P. acnes) is a growing phenomenon in the wake of widespread use of topical and systemic antibiotics for acne vulgaris. Benzoyl peroxide has a proven track record of safety and efficacy, and can decrease reliance
Emil A Tanghetti et al.
Dermatologic clinics, 27(1), 17-24 (2008-11-06)
Benzoyl peroxide (BPO) is the most widely used topical acne treatment, with significant antibacterial, antikeratolytic, and comedolytic activity. It has been shown to be extremely effective as monotherapy and in combination with antibiotics or retinoids for managing comedonal and inflammatory
Gillian M Keating
American journal of clinical dermatology, 12(6), 407-420 (2011-10-05)
Adapalene 0.1%/benzoyl peroxide 2.5% gel (Epiduo™, Tactuo™) is the only fixed-dose combination product available that combines a topical retinoid with benzoyl peroxide; it targets three of the four main pathophysiologic factors in acne. This article reviews the therapeutic efficacy and
Kate McKeage et al.
American journal of clinical dermatology, 9(3), 193-204 (2008-04-24)
Clindamycin 1%/benzoyl peroxide 5% (BenzaClin) is a combination gel indicated for use twice daily, or as directed by a physician, for the topical treatment of inflammatory and noninflammatory lesions of acne vulgaris. In well designed clinical trials in patients with
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