V000702
Benzoyl peroxide
72.0-80.0%
Synonym(s):
Dibenzoyl peroxide
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About This Item
Linear Formula:
(C6H5CO)2O2
CAS Number:
Molecular Weight:
242.23
PubChem Substance ID:
Beilstein/REAXYS Number:
984320
MDL number:
InChI key
OMPJBNCRMGITSC-UHFFFAOYSA-N
SMILES string
O=C(OOC(=O)c1ccccc1)c2ccccc2
InChI
1S/C14H10O4/c15-13(11-7-3-1-4-8-11)17-18-14(16)12-9-5-2-6-10-12/h1-10H
grade
synthesis grade
assay
72.0-80.0%
autoignition temp.
176 °F
mp
105 °C (lit.)
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Application
Widely used initiator, curing agent, and cross-linking agent in polymerization processes.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1
Storage Class
4.1A - Other explosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Tarek Fakhouri et al.
Journal of drugs in dermatology : JDD, 8(7), 657-661 (2009-07-11)
Antibiotic resistance of Propionibacterium acnes (P. acnes) is a growing phenomenon in the wake of widespread use of topical and systemic antibiotics for acne vulgaris. Benzoyl peroxide has a proven track record of safety and efficacy, and can decrease reliance
A L Kraus et al.
Regulatory toxicology and pharmacology : RTP, 21(1), 87-107 (1995-02-01)
Topical benzoyl peroxide has been used in the treatment of acne for over 30 years, with no reports of adverse effects that could be related to skin carcinogenesis. Two case-control epidemiological studies have found a lack of association between the
Kate McKeage et al.
American journal of clinical dermatology, 9(3), 193-204 (2008-04-24)
Clindamycin 1%/benzoyl peroxide 5% (BenzaClin) is a combination gel indicated for use twice daily, or as directed by a physician, for the topical treatment of inflammatory and noninflammatory lesions of acne vulgaris. In well designed clinical trials in patients with
Gina A Taylor et al.
American journal of clinical dermatology, 5(4), 261-265 (2004-08-11)
Benzoyl peroxide, with its broad-spectrum antimicrobial activity, is among the most widely used topical agents in the treatment of inflammatory acne vulgaris. Benzoyl peroxide is marketed either alone or in combination with other topical antibiotics; namely, erythromycin and clindamycin. The
Emil A Tanghetti et al.
Dermatologic clinics, 27(1), 17-24 (2008-11-06)
Benzoyl peroxide (BPO) is the most widely used topical acne treatment, with significant antibacterial, antikeratolytic, and comedolytic activity. It has been shown to be extremely effective as monotherapy and in combination with antibiotics or retinoids for managing comedonal and inflammatory
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