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Merck
CN

V000961

Sigma-Aldrich

Neutral Red

Synonym(s):

3-Amino-7-dimethylamino-2-methylphenazine hydrochloride, Basic Red 5, Toluylene red

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About This Item

Empirical Formula (Hill Notation):
C15H17ClN4
CAS Number:
553-24-2
Molecular Weight:
288.78
Colour Index Number:
50040
Beilstein:
3918740
EC Number:
209-035-8
MDL number:
MFCD00012651
PubChem Substance ID:
329828291

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pH

6.8-8.0, red to yellow

mp

290 °C (dec.) (lit.)

SMILES string

Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1

InChI

1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H

InChI key

PGSADBUBUOPOJS-UHFFFAOYSA-N

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Application

Useful as an indicator for preparing neutral red paper, and as a biological stain.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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[Vital staining of lysosomes and other cell organelles of the rat with neutral red (a summary)].
J Winckler
Acta histochemica. Supplementband, 16, 15-22 (1976-01-01)
C Svendsen et al.
Ecotoxicology and environmental safety, 57(1), 20-29 (2003-12-09)
The ability of biomarkers to integrate effects of chemicals on biota has lead to increased calls for their application in assessing the status of polluted ecosystems. In tandem there has been an increase in our knowledge of the ecophysiological responses
Maqusood Ahamed et al.
Chemosphere, 135, 278-288 (2015-05-13)
Nickel ferrite nanoparticles (NPs) have received much attention for their potential applications in biomedical fields such as magnetic resonance imaging, drug delivery and cancer hyperthermia. However, little is known about the toxicity of nickel ferrite NPs at the cellular and
V Zuang
Alternatives to laboratory animals : ATLA, 29(5), 575-599 (2001-10-18)
The neutral red release (NRR) assay is a cytotoxicity test that can be used to measure the immediate toxic effects of test substances on the cell membrane, resulting in the leaking of intracellular contents. The assay has already been used
Intracellular pH determination by absorption spectrophotometry of neutral red.
J C LaManna
Metabolic brain disease, 2(3), 167-182 (1987-09-01)
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