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Merck
CN

V001021

Sigma-Aldrich

Brilliant Blue G

Synonym(s):

Acid blue 90, Coomassie Brilliant Blue G

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About This Item

Empirical Formula (Hill Notation):
C47H48N3NaO7S2
CAS Number:
Molecular Weight:
854.02
Colour Index Number:
42655
Beilstein:
5230822
EC Number:
MDL number:
PubChem Substance ID:
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SMILES string

[Na+].CCOc1ccc(Nc2ccc(cc2)C(\c3ccc(cc3C)N(CC)Cc4cccc(c4)S([O-])(=O)=O)=C5\C=CC(\C=C5C)=[N+](\CC)Cc6cccc(c6)S([O-])(=O)=O)cc1

InChI

1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1

InChI key

RWVGQQGBQSJDQV-UHFFFAOYSA-M

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Biochem/physiol Actions

P2X7 purinergic receptor antagonist.

Legal Information

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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V S Gasparov et al.
Biokhimiia (Moscow, Russia), 59(6), 763-777 (1994-06-01)
Possible applications of the Coomassie brilliant blue G-250 dye method for protein assay are reviewed. The physico-chemical and optical properties of the dye are considered in detail. The data on the protein-binding mechanism are generalized. Modifications of the Coomassie blue
Felipe P P Almeida et al.
JAMA ophthalmology, 133(1), 85-88 (2014-10-17)
This case report describes a man who developed retinal changes in his right eye associated with brilliant blue G migration into the subretinal space during 2 years of follow-up. The patient's best-corrected visual acuity in the right eye was 20/70
Yüksel Totan et al.
The British journal of ophthalmology, 99(1), 75-80 (2014-08-06)
To evaluate the potential efficacy and safety of inner limiting membrane (ILM) staining with brilliant blue G (BBG) under air infusion. 63 patients, treated by one surgeon with macular hole or idiopathic epiretinal membrane were evaluated prospectively. BBG was applied
Mikito Owa et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9461-9466 (2014-07-01)
Outer arm dynein (OAD) in cilia and flagella is bound to the outer doublet microtubules every 24 nm. Periodic binding of OADs at specific sites is important for efficient cilia/flagella beating; however, the molecular mechanism that specifies OAD arrangement remains

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