V001671
Tiron
Synonym(s):
4,5-Dihydroxy-1,3-benzenedisulfonic acid disodium salt, Pyrocatechol-3,5-disulfonic acid disodium salt
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About This Item
Empirical Formula (Hill Notation):
C6H4Na2O8S2
CAS Number:
Molecular Weight:
314.20
EC Number:
205-741-5
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4629740
InChI
1S/C6H6O8S2.2Na/c7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;/h1-2,7-8H,(H,9,10,11)(H,12,13,14);;/q;2*+1/p-2
InChI key
ISWQCIVKKSOKNN-UHFFFAOYSA-L
SMILES string
[Na+].[Na+].Oc1cc(cc(c1O)S([O-])(=O)=O)S([O-])(=O)=O
Legal Information
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Nai-Yuan Lee et al.
The Chinese journal of physiology, 53(5), 294-298 (2011-07-29)
A rise in cytosolic free Ca2+ is the immediate trigger for contraction in heart muscle. In the present study, we investigated changes of intracellular Ca2+ increased by potassium chloride (KCl) and phenylephrine (PE) under hyperglycemia in rat heart myoblast H9c2
Yong Fang et al.
The Australasian journal of dermatology, 53(3), 172-180 (2012-06-28)
Free radicals and reactive oxygen species (ROS), which are generated by UV irradiation, may induce an irreversible growth arrest similar to senescence. Tiron, 4,5-dihydroxy-1,3-benzene disulfonic acid, is a widely used antioxidant to rescue ROS-evoked cell death. The aim of the
D D Guimarães et al.
Clinical and experimental pharmacology & physiology, 39(4), 373-378 (2012-01-31)
In pathological conditions, such as hypertension, there is impairment in the autonomic control of blood pressure resulting in changes in baroreflex sensitivity. In the present study we tested the hypothesis that acute superoxide scavenging would restore the depressed baroreflex sensitivity
Taciana F Gomes et al.
Talanta, 102, 53-58 (2012-11-28)
A flow system with zone merging and zone trapping in the main reactor was proposed. The sample and reagent inserted aliquots merge together and the resulting zone is directed towards a displaceable reactor inside which its most concentrated portion is
Jennifer L McCord et al.
Journal of applied physiology (Bethesda, Md. : 1985), 111(4), 971-979 (2011-07-09)
In decerebrate rats, we reported previously that the exercise pressor reflex arising from a limb whose femoral artery was occluded for 72 h before the experiment was significantly higher than the exercise pressor reflex arising from a contralateral freely perfused
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