Name: <I>N</I>-Hydroxysulfosuccinimide sodium salt
Brand: VETEC

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About This Item

Empirical Formula (Hill Notation):

C₄H₄NNaO₆S

CAS Number:

106627-54-7

Molecular Weight:

217.13

Beilstein:

6359129

MDL number:

MFCD00043100

UNSPSC Code:

12352005

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Quality Level

100

Assay

≥98% (HPLC)

form

solid

composition

carbon, 21.57-22.68 (anhydrous)
nitrogen, 6.28-6.61 (anhydrous)

reaction suitability

reaction type: Addition Reactions

impurities

≤4 water

application(s)

peptide synthesis

functional group

imide
sulfonic acid

SMILES string

[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O

InChI

1S/C4H5NO6S.Na/c6-3-1-2(12(9,10)11)4(7)5(3)8;/h2,8H,1H2,(H,9,10,11);/q;+1/p-1

InChI key

RPENMORRBUTCPR-UHFFFAOYSA-M

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General description

N-Hydroxysulfosuccinimide sodium salt is a water-soluble sulfonated analog of N-hydroxysuccinimide. It can undergo a coupling reaction with carboxylic acids in the presence of carbodiimides such as 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(EDC) to form hydrophilic N-hydroxysulfosuccinimide active esters. These esters are useful in protein cross-linking experiments.

Application

Sulfo-NHS is used for preparing hydrophilic active esters, e.g. for crosslinking agents.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number

WXBF6032V

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