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Merck
CN

V900086

Thioacetamide

98%, Vetec, reagent grade

Synonym(s):

Ethanethioamide

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About This Item

Linear Formula:
CH3CSNH2
CAS Number:
Molecular Weight:
75.13
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
200-541-4
Beilstein/REAXYS Number:
506006
MDL number:
Assay:
98%
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Product Name

Thioacetamide, Vetec, reagent grade, 98%

InChI key

YUKQRDCYNOVPGJ-UHFFFAOYSA-N

InChI

1S/C2H5NS/c1-2(3)4/h1H3,(H2,3,4)

SMILES string

CC(N)=S

grade

reagent grade

product line

Vetec

assay

98%

mp

108-112 °C (lit.)

functional group

amine

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Hong Ling et al.
PloS one, 8(1), e54499-e54499 (2013-01-26)
Considerable evidence has demonstrated that transforming growth factor β (TGF-β) plays a key role in hepatic fibrosis, the final common pathway for a variety of chronic liver diseases leading to liver insufficiency. Although a few studies have reported that blocking
Heather Hajovsky et al.
Chemical research in toxicology, 25(9), 1955-1963 (2012-08-08)
The hepatotoxicity of thioacetamide (TA) has been known since 1948. In rats, single doses cause centrolobular necrosis accompanied by increases in plasma transaminases and bilirubin. To elicit these effects, TA requires oxidative bioactivation, leading first to its S-oxide (TASO) and
Chiung-Kuei Huang et al.
Hepatology (Baltimore, Md.), 57(4), 1550-1563 (2012-11-15)
Transplantation of bone marrow mesenchymal stem cells (BM-MSCs) has been considered as an alternative therapy, replacing liver transplantation in clinical trials, to treat liver cirrhosis, an irreversible disease that may eventually lead to liver cancer development. However, low survival rate
Peng Zhan et al.
Archives of pharmacal research, 35(6), 975-986 (2012-08-09)
In continuation of our endeavor to develop new, potent, selective and less toxic antiviral agents, a novel series of 2-(2-amino/chloro-4-(2,4-dibromophenyl) thiazol-5-ylthio)acetamide derivatives was synthesized via an expeditious route and evaluated for their anti-HIV activities against wild-type virus and clinically relevant
Mladen I Yovchev et al.
Hepatology (Baltimore, Md.), 59(1), 284-295 (2013-07-11)
Considerable progress has been made in developing antifibrotic agents and other strategies to treat liver fibrosis; however, significant long-term restoration of functional liver mass has not yet been achieved. Therefore, we investigated whether transplanted hepatic stem/progenitor cells can effectively repopulate

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