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About This Item
Linear Formula:
CH3CSNH2
CAS Number:
Molecular Weight:
75.13
Beilstein:
506006
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
Product Name
Thioacetamide, Vetec™, reagent grade, 98%
grade
reagent grade
product line
Vetec™
Assay
98%
mp
108-112 °C (lit.)
functional group
amine
SMILES string
CC(N)=S
InChI
1S/C2H5NS/c1-2(3)4/h1H3,(H2,3,4)
InChI key
YUKQRDCYNOVPGJ-UHFFFAOYSA-N
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Heather Hajovsky et al.
Chemical research in toxicology, 25(9), 1955-1963 (2012-08-08)
The hepatotoxicity of thioacetamide (TA) has been known since 1948. In rats, single doses cause centrolobular necrosis accompanied by increases in plasma transaminases and bilirubin. To elicit these effects, TA requires oxidative bioactivation, leading first to its S-oxide (TASO) and
Peng Zhan et al.
Bioorganic & medicinal chemistry, 20(23), 6795-6802 (2012-10-27)
The present work is an extension of our ongoing efforts towards the development and identification of new molecules with anti-HIV activity which have previously led to the discovery of arylazolylthioacetanilides as highly active NNRTIs. In this article, a series of
Suzy M Salama et al.
BMC complementary and alternative medicine, 13, 56-56 (2013-03-19)
Hepatology research has focused on developing traditional therapies as pharmacological medicines to treat liver cirrhosis. Thus, this study evaluated mechanisms of the hepatoprotective activity of Curcuma longa rhizome ethanolic extract (CLRE) on thioacetamide-induced liver cirrhosis in rats. The hepatoprotective effect
Mladen I Yovchev et al.
Hepatology (Baltimore, Md.), 59(1), 284-295 (2013-07-11)
Considerable progress has been made in developing antifibrotic agents and other strategies to treat liver fibrosis; however, significant long-term restoration of functional liver mass has not yet been achieved. Therefore, we investigated whether transplanted hepatic stem/progenitor cells can effectively repopulate
Cun-hua Shao et al.
The Journal of surgical research, 186(1), 408-416 (2013-09-28)
Recent studies have demonstrated that bone marrow-derived mesenchymal stem cells (BM-MSCs) can potentially revert liver fibrosis, but it is not known if preparative hepatic irradiation (HIR) contributes to the therapeutic effect of transplanted BM-MSCs. In this study, we investigate the
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