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Merck
CN

V900250

2,4,6-Trimethylpyridine

98%, Vetec™, reagent grade

Synonym(s):

2,4,6-Collidine, sym-Collidine

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About This Item

Empirical Formula (Hill Notation):
C8H11N
CAS Number:
108-75-8
Molecular Weight:
121.18
UNSPSC Code:
12352100
PubChem Substance ID:
329829676
EC Number:
203-613-3
Beilstein/REAXYS Number:
107283
MDL number:
MFCD00006338
Assay:
98%

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Product Name

2,4,6-Trimethylpyridine, Vetec™, reagent grade, 98%

InChI key

BWZVCCNYKMEVEX-UHFFFAOYSA-N

InChI

1S/C8H11N/c1-6-4-7(2)9-8(3)5-6/h4-5H,1-3H3

SMILES string

Cc1cc(C)nc(C)c1

grade

reagent grade

product line

Vetec™

assay

98%

bp

171-172 °C (lit.)

mp

−43 °C (lit.)

density

0.917 g/mL at 25 °C (lit.)

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Application

Tissue fixative for electron microscopy.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameSkull and crossbones
GHS02,GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

131.0 °F - closed cup

flash_point_c

55 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
WXBB1470V
MKBH3498V

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G Rodríguez de Lores Arnaiz et al.
Neuroscience letters, 108(3), 309-313 (1990-01-22)
Previous histochemical studies have demonstrated that collidine abolished the osmiophilia and the chromaffin reaction of the synaptic vesicles, an effect which was ascribed to the release of stored neurotransmitters. Other studies indicated a relationship between the inhibition of Na+,K(+)-ATPase and
Jeffrey R Kanofsky et al.
Journal of photochemistry and photobiology. B, Biology, 87(2), 124-129 (2007-04-25)
Prior work using cell culture has shown that certain synthetic carotenoid derivatives are more effective than natural carotenoids in preventing photosensitized cell killing. These carotenoid derivatives are either cationic or are weak bases. We have now found that of one
J Hasegawa et al.
Journal of pharmaceutical sciences, 73(4), 442-445 (1984-04-01)
The pKa of verapamil was determined by measuring the partition coefficient of verapamil between n-heptane and aqueous buffer solution at various pH values. The magnitude of the effects of ionic strength or temperature on the pKa of verapamil was in
Christa A Currie et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 824(1-2), 201-205 (2005-08-09)
Microchip capillary electrophoresis (CE), coupled with indirect fluorescence detection was investigated for estimating the pK(a) values of non-fluorescent compounds. The CE method is based on the differences in electrophoretic mobility of the analyte as a function of the pH of
J L Tomsig et al.
Histochemistry, 87(1), 21-25 (1987-01-01)
Rat pineal nerve endings contain a population of small and of large synaptic vesicles that are either electron lucent or have electron-dense cores. It has been reported that their osmiophilia is eliminated when collidine buffer is used in the fixation
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