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Merck
CN

V900437

Thymine

Vetec, reagent grade, 99%

Synonym(s):

2,4-Dihydroxy-5-methylpyrimidine, 5-Methyluracil

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About This Item

Empirical Formula (Hill Notation):
C5H6N2O2
CAS Number:
Molecular Weight:
126.11
EC Number:
200-616-1
UNSPSC Code:
41106305
PubChem Substance ID:
Beilstein/REAXYS Number:
117880
MDL number:
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Product Name

Thymine, Vetec, reagent grade, 99%

InChI key

RWQNBRDOKXIBIV-UHFFFAOYSA-N

InChI

1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)

SMILES string

CC1=CNC(=O)NC1=O

grade

reagent grade

product line

Vetec

assay

99%

mp

~320 °C (dec.) (lit.)

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Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Lakshminarayan M Iyer et al.
Nucleic acids research, 41(16), 7635-7655 (2013-07-03)
Discovery of the TET/JBP family of dioxygenases that modify bases in DNA has sparked considerable interest in novel DNA base modifications and their biological roles. Using sensitive sequence and structure analyses combined with contextual information from comparative genomics, we computationally
Cai Shen et al.
Chemical communications (Cambridge, England), 49(5), 508-510 (2012-12-04)
Supramolecular patterns formed by adsorption from a liquid of nucleobase-terminated molecular rods on a graphite surface were investigated by scanning tunneling microscopy.
M Weinfeld et al.
Progress in nucleic acid research and molecular biology, 68, 139-149 (2001-09-14)
The toxic and mutagenic effects of ionizing radiation are believed to be caused by damage to cellular DNA. We have made use of a novel immunoassay for thymine glycol to examine the removal of this lesion from the DNA of
Paulina Prorok et al.
PloS one, 7(12), e51776-e51776 (2012-12-20)
Oxygen free radicals induce lipid peroxidation (LPO) that damages and breaks polyunsaturated fatty acids in cell membranes. LPO-derived aldehydes and hydroxyalkenals react with DNA leading to the formation of etheno(ε)-bases including 1,N(6)-ethenoadenine (εA) and 3,N(4)-ethenocytosine (εC). The εA and εC
Ibtissam Talhaoui et al.
Nucleic acids research, 41(2), 912-923 (2012-12-05)
Hydroxyl radicals predominantly react with the C(8) of purines forming 7,8-dihydro-8-oxoguanine (8oxoG) and 7,8-dihydro-8-oxoadenine (8oxoA) adducts, which are highly mutagenic in mammalian cells. The majority of oxidized DNA bases are removed by DNA glycosylases in the base excision repair pathway.

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