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Merck
CN

V900570

2,3,5,6-Tetramethylpyrazine

Vetec, reagent grade, 98%

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About This Item

Empirical Formula (Hill Notation):
C8H12N2
CAS Number:
Molecular Weight:
136.19
EC Number:
214-391-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
113100
MDL number:
Assay:
98%
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grade

reagent grade

product line

Vetec

assay

98%

bp

190 °C (lit.)

mp

77-80 °C (lit.)

SMILES string

Cc1nc(C)c(C)nc1C

InChI

1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3

InChI key

FINHMKGKINIASC-UHFFFAOYSA-N

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

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signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Xuesong Zhang et al.
Journal of cellular physiology (2019-02-17)
Inadequate oxygen supply is probably one of the most important pathophysiological mechanisms of cardiomyocyte damage in ischemic heart disease. Tetramethylpyrazine (TMP, also known as ligustrazine) is the main active ingredient isolated from the rhizome of Ligusticum chuanxiong Hort. A previous
Ling Guo et al.
Molecules (Basel, Switzerland), 17(5), 5412-5421 (2012-05-10)
The aim of the study was to determine the effect of tetramethylpyrazine phosphate tablets (TPT), a Chinese medicine used for cardiovascular disease, on immunity activity and oxidative injury in rats. Heart failure (HF) was induced by isoproterenol (ISO). After the
Feng Zhang et al.
Toxicology and applied pharmacology, 265(1), 51-60 (2012-10-02)
Hepatic fibrosis represents a frequent event following chronic insult to trigger wound healing reactions with accumulation of extracellular matrix (ECM) in the liver. Activation of hepatic stellate cells (HSCs) is the pivotal event during liver fibrogenesis. Compelling evidence indicates that



Global Trade Item Number

SKUGTIN
V900570-25G04061833462430