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Merck
CN

V900833

Hyaluronidase from bovine testes

Vetec™, reagent grade

Synonym(s):

Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase

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About This Item

CAS Number:
37326-33-3
UNSPSC Code:
12352202
EC Number:
253-464-3
MDL number:
MFCD00131351
EC Number:
3.2.1.35 (BRENDA, IUBMB)

Key Documents

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Product Name

Hyaluronidase from bovine testes, Vetec™, reagent grade

biological source

bovine testis

conjugate

conjugate (Glucosaminoglycan)

grade

reagent grade

product line

Vetec™

form

powder

specific activity

≥750 units/mg solid

storage temp.

−20°C

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Biochem/physiol Actions

Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression.
These enzymes randomly cleave β-N-acetylhexosamine-[1→4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.

Other Notes

One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37 deg C in a 2.0 ml reaction mixture.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H334

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7972V
WXBF6553V
WXBF3736V
WXBF4865V
WXBF2507V

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Hasnaa Yaigoub et al.
Frontiers in cell and developmental biology, 10, 822275-822275 (2022-05-28)
Objective: Establishment of an efficient method of preparing human kidney single cell suspension, using a very small amount of tissue puncture. Methods: Samples of human kidney tissue puncture were cut into pieces, and then 80 μL of the digestive enzyme were
Xuebo Pan et al.
Cell metabolism, 27(6), 1323-1337 (2018-05-01)
Fibroblast growth factor 21 (FGF21) is a metabolic hormone with pleiotropic effects on glucose and lipid metabolism and insulin sensitivity. However, the role of FGF21 in hypertension remains elusive. Here we show that FGF21 deficiency significantly exacerbates angiotensin II-induced hypertension
Xiaoying Fan et al.
PLoS biology, 18(12), e3001017-e3001017 (2020-12-31)
The development of next generation sequencing (NGS) platform-based single-cell RNA sequencing (scRNA-seq) techniques has tremendously changed biological researches, while there are still many questions that cannot be addressed by them due to their short read lengths. We developed a novel
Yan Jiang et al.
Journal of assisted reproduction and genetics, 30(9), 1175-1179 (2013-08-31)
To study the efficacy of percutaneous epididymal sperm aspiration (PESA) in combination with short time insemination to treat infertile men with obstructive azoospermia (OA). Paired randomized controlled trial in which each couple's cohort of oocytes was divided into two equal
Brandon Buckway et al.
International journal of pharmaceutics, 456(1), 202-211 (2013-08-13)
Delivery of macromolecules to pancreatic cancer is inhibited by a dense extracellular matrix composed of hyaluronic acid, smooth muscle actin and collagen fibers. Hyaluronic acid causes a high intratumoral fluidic pressure which prevents diffusion and penetration into the pancreatic tumor.
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