CN
Search Within
110-87-2
Applied Filters:
Keyword:'110-87-2'
Showing 1-30 of 40 results for "110-87-2" within Papers
Yingkui Yang et al.
Molecular pharmacology, 64(1), 94-103 (2003-06-20)
Agouti-related protein (AGRP) is an endogenous antagonist of the melanocortin-4 receptor (MC4R) that functions in the hypothalamic control of feeding behavior. Our previous studies have suggested that in addition to exoloops 2 and 3, several transmembrane domains of MC4R may
Maura Camozzi et al.
The Journal of biological chemistry, 281(32), 22605-22613 (2006-06-14)
Long-pentraxin 3 (PTX3) is a soluble pattern recognition receptor with non-redundant functions in inflammation and innate immunity. PTX3 comprises a pentraxin-like C-terminal domain involved in complement activation via C1q interaction and an N-terminal extension with unknown functions. PTX3 binds fibroblast
M Potter et al.
Genomics, 2(3), 257-262 (1988-04-01)
Early-passage skin fibroblasts from different inbred and congenic strains of mice were X-irradiated (1 Gy), and the number of chromatid breaks was determined at 2.0 h after irradiation. The cells from DBA/2N, C3H/HeN, STS/A, C57BL/6N, BALB/cJ, and AKR/N had 25
Mohamed N Aboul-Enein et al.
European journal of medicinal chemistry, 47(1), 360-369 (2011-11-29)
A series of stiripentol (STP) analogues namely, 2-[(1E)-1-(1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ylidene]-N-(aryl/H)hydrazinecarboxamides 7a-h, (±)-(5RS)-N-(aryl/H)-(1,3-benzodioxol-5-yl)-3-tert-butyl-4,5-dihydro-1H-pyrazole-1-carboxamides (±)-8a-h, and (±)-[(5RS)-(1,3-benzodioxol-5-yl)-3-tert-butyl-4,5-dihydro-1H-pyrazol-1-yl](aryl)methanones (±)-13a-f was synthesized by adopting appropriate synthetic routes and was pharmacologically evaluated in the preliminary anticonvulsant screens. The selected bioactive new chemical entities were subjected to ED(50)
Elyssa B Margolis et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(44), 14707-14716 (2014-10-31)
The ventral tegmental area (VTA) is required for the rewarding and motivational actions of opioids and activation of dopamine neurons has been implicated in these effects. The canonical model posits that opioid activation of VTA dopamine neurons is indirect, through
Anne Marie Comeau et al.
Pediatrics, 113(6), 1573-1581 (2004-06-03)
Newborn screening for cystic fibrosis (CF) provides a model to investigate the implications of applying multiple-mutation DNA testing in screening for any disorder in a pediatric population-based setting, where detection of affected infants is desired and identification of unaffected carriers
Nitish R Mahapatra et al.
Journal of neurochemistry, 99(1), 119-133 (2006-09-22)
The molecular basis of neuroendocrine-specific expression of chromogranin B gene (Chgb) has remained elusive. Utilizing wild-type and mutant Chgb promoter/luciferase reporter constructs, this study established a crucial role for the cAMP response element (CRE) box at -102/-95 bp in endocrine
Deidra J H Mountain et al.
The Journal of surgical research, 184(1), 619-627 (2013-06-19)
Testosterone deficiency has been associated with an increased risk of vascular disease. Matrix metalloproteinases (MMPs) have been implicated in vascular remodeling. Our group has demonstrated an association between female hormones and MMP-modulated intimal hyperplasia. In the present study, we investigated testosterone
S C Garman et al.
Journal of molecular biology, 311(5), 1049-1062 (2001-09-05)
We have solved the structure of the human high affinity IgE receptor, Fc epsilon RI alpha, in six different crystal forms, showing the structure in 15 different chemical environments. This database of structures shows no change in the overall shape
F Cui et al.
Wei sheng wu xue bao = Acta microbiologica Sinica, 38(4), 300-303 (2003-01-29)
Cephradine was synthesized by gamma-alumina-immobilized form of the penicillin G acylase of Bacillus megaterium with D-phenyglycine methylester hydrochloride (CH DGME.HCl) as acyl donor and 7-aminodeacetoxycephalosporanic acid (7-ADCA) as acyl acceptor. 0.1 g of 7-ADCA was dissolved by adding 2.5 ml
M Wallner et al.
Receptors & channels, 3(3), 185-199 (1995-01-01)
cDNAs encoding functional maxi KCa channel alpha-subunits (hslo) were cloned from human myometrium. Northern blot analysis revealed a high abundance of mRNA in human uterine smooth muscle. Calcium- and voltage-activated K+ currents were recorded from Xenopus laevis oocytes injected with
Harold M Aukema et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(2), 298-300 (2002-12-20)
Cytosolic phospholipase A2 (cPLA2), cyclooxygenase-1 (COX-1), and cyclooxygenase-2 (COX-2) regulate the formation of physiologically active prostaglandins, the production of which is known to be elevated in several renal disorders. We studied the relevance of these enzymes in polycystic kidney disease
Eva Martinez-Balibrea et al.
European journal of cancer (Oxford, England : 1990), 44(9), 1229-1237 (2008-05-02)
We studied the role of TS (5'VNTR, 5'SNP and 3'UTR), XRCC1-399, XPD-751, ERCC1-118 and XRCC3-241 genetic polymorphisms in tailoring fluroropyrimidine/oxaliplatin treatment. For this purpose, 110 XELOX (capecitabine/oxaliplatin)- or FUOX (fluorouracil/oxaliplatin)-treated metastatic colorectal cancer patients were selected prospectively for genotyping. In
Violet Shen et al.
Journal of pediatric hematology/oncology, 25(1), 38-45 (2003-01-25)
To evaluate the safety and efficacy of alteplase for restoring function to occluded central venous catheters in a pediatric population. A phase III, open-label, single-arm, multicenter trial was performed in 995 adult and pediatric patients with dysfunctional nondialysis catheters and
Faraj Hijaz et al.
Journal of food science, 72(5), C253-C257 (2007-11-13)
The indophenol method, ammonia ion selective electrode (ISE), Reflectoquant(R) test strips, and salicylate methods were evaluated to determine those that can be used for in-plant rapid testing of meat contaminated by ammonia refrigerant leaks. Ground eye of round beef samples
F Dorey et al.
Clinical endocrinology, 32(2), 221-228 (1990-02-01)
Selective pituitary resistance to thyroid hormone (PRTH) is responsible for thyrotoxicosis due to inappropriate secretion of TSH. The TSH suppressive action of D-thyroxine (DT4) has been previously documented in euthyroid and hypothyroid subjects. This prompted us to treat with DT4
Ling Mei et al.
International journal of pharmaceutics, 474(1-2), 95-102 (2014-08-21)
Delivering chemotherapeutics by nanoparticles into tumor was influenced by at least two factors: specific targeting and highly efficient penetrating of the nanoparticles. In this study, two targeting ligands, angiopep-2 and activatable cell penetrating peptide (ACP), were functionalized onto nanoparticles for
Carol Durno et al.
Gastroenterology, 123(6), 1857-1864 (2002-11-28)
Pancreatitis is known to occur in some patients with cystic fibrosis (CF), but the prevalence, natural history, and genotypic basis are unclear. We examined a well-defined cohort of patients with CF to answer these questions. Patients with CF were identified
Fabrício E Bortot Coelho et al.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering, 56(3), 289-302 (2021-01-15)
Galvanizing industries generate large amounts of effluents rich in toxic and carcinogenic chromium(VI) species. Effective and sustainable treatments are required to comply with environmental regulations. This work focused on the development of innovative treatments for Cr(VI) by its removal from
Pierre C Qian et al.
Journal of hypertension, 37(10), 2083-2092 (2019-04-30)
Clinical studies of transcatheter radiofrequency renal denervation for treating hypertension have been hampered by the lack of consistent denervation efficacy. We aimed to demonstrate the short-term efficacy and safety of transcatheter microwave renal denervation. A novel 7F microwave system was
S A Romanski et al.
Mayo Clinic proceedings, 68(5), 419-426 (1993-05-01)
We compared the sensitivity of aurin tricarboxylic acid (ATA) or acid solochrome azurine (ASA) for detecting bone aluminum histochemically in 87 biopsy specimens obtained between 1983 and 1987 from 84 patients receiving dialysis therapy. Two consecutive biopsy sections were stained
Bai Youpeng et al.
Hypertension research : official journal of the Japanese Society of Hypertension, 33(10), 1066-1070 (2010-07-29)
The etiology and pathogenesis of preeclampsia remain unclear. Little is known about the possible impact of adiponectin gene polymorphisms on the pathogenesis of preeclampsia. In this study, we analyzed the association of two adiponectin single-nucleotide polymorphisms (SNPs) with preeclampsia. One
Liangming Zhang et al.
Journal of pineal research, 49(4), 364-372 (2010-08-27)
Adipogenesis and osteogenesis, a reciprocal relationship in bone marrow, are complex processes including proliferation of precursor cells, commitment to the specific lineage, and terminal differentiation. Accumulating evidence from in vitro and in vivo studies suggests that melatonin affects terminal differentiation
Biman B Mandal et al.
Nanotechnology, 20(35), 355101-355101 (2009-08-13)
In recent times self-assembled micellar nanoparticles have been successfully employed in tissue engineering for targeted drug delivery applications. In this review, silk sericin protein from non-mulberry Antheraea mylitta tropical tasar silk cocoons was blended with pluronic F-127 and F-87 in
Slaheddine Fattoum et al.
Hemoglobin, 28(3), 177-187 (2004-10-16)
The present study attempts to delineate the spectrum of beta-thalassemia (thal) mutations in Tunisia by studying a large population from different parts of the country. A total of 285 unrelated subjects, 190 of whom had beta-thal major, 72 with Hb
Nilofar Khan et al.
The Journal of general physiology, 132(2), 223-238 (2008-07-30)
We examined the concentration dependence of currents through Ca(V)3.1 T-type calcium channels, varying Ca(2+) and Ba(2+) over a wide concentration range (100 nM to 110 mM) while recording whole-cell currents over a wide voltage range from channels stably expressed in
Teresa C Delgado et al.
American journal of physiology. Endocrinology and metabolism, 304(4), E384-E391 (2012-12-06)
Dietary fructose can benefit or hinder glycemic control, depending on the quantity consumed, and these contrasting effects are reflected by alterations in postprandial hepatic glycogen synthesis. Recently, we showed that ²H enrichment of glycogen positions 5 and 2 from deuterated
Justin H Turner et al.
The Journal of biological chemistry, 279(17), 17027-17037 (2004-01-31)
The serotonin 5-HT(1A) receptor couples to heterotrimeric G proteins and intracellular second messengers, yet no studies have investigated the possible role of additional receptor-interacting proteins in 5-HT(1A) receptor signaling. We have found that the ubiquitous Ca(2+)-sensor calmodulin (CaM) co-immunoprecipitates with
Alina Weissmann-Brenner et al.
International journal of oncology, 40(6), 2097-2103 (2012-03-20)
There is emerging evidence for the prognostic role of various microRNA (miRNA) molecules in colon cancer. The aim of this study was therefore to compare the miRNA profiles in the primary tumor of patients with recurrent and non-recurrent colon cancer.
Flor-Anita Corredor et al.
BMC genetics, 21(1), 28-28 (2020-03-14)
Reproductive performance is critical for efficient swine production. Recent results indicated that vulva size (VS) may be predictive of reproductive performance in sows. Study objectives were to estimate genetic parameters, identify genomic regions associated, and estimate genomic prediction accuracies (GPA)
Page 1 of 2