Search Within
168149
Applied Filters:
Keyword:'168149'
Showing 31-60 of 504 results for "168149" within Papers
S Lopa et al.
European cells & materials, 27, 298-311 (2014-04-25)
Cell-based therapies have recently been proposed for the treatment of degenerative articular pathologies, such as early osteoarthritis, with an emphasis on autologous mesenchymal stem cells (MSCs), as an alternative to terminally differentiated cells. In this study, we performed a donor-matched
Pamela C Rosato et al.
Journal of virology, 88(17), 9991-10001 (2014-06-20)
Herpes simplex virus 1 (HSV-1) establishes lifelong latent infections in the sensory neurons of the trigeminal ganglia (TG), wherein it retains the capacity to reactivate. The interferon (IFN)-driven antiviral response is critical for the control of HSV-1 acute replication. We
Fabio Andres Castillo Martinez et al.
The Journal of dairy research, 82(3), 350-355 (2015-04-09)
Bacteriocins are natural compounds used as food biopreservatives instead of chemical preservatives. Bifidobacterium animalis subsp. lactis (Bifid. lactis) was shown to produce a bacteriocin-like inhibitory substance (BLIS) able to inhibit the growth of Listeria monocytogenes selected as an indicator microorganism.
Katie L I M Blundell et al.
The Biochemical journal, 459(3), 525-538 (2014-02-20)
In Streptomyces lividans an extracytoplasmic copper-binding Sco protein plays a role in two unlinked processes: (i) initiating a morphological development switch and (ii) facilitating the co-factoring of the CuA domain of CcO (cytochrome c oxidase). How Sco obtains copper once
Moshit Lindzen et al.
The Journal of biological chemistry, 281(9), 5947-5955 (2005-12-24)
Interactions of rat FXYD4 (corticosteroid hormone-induced factor (CHIF)), FXYD2 (gamma), or FXYD1 (phospholemman (PLM)) proteins with rat alpha1 subunits of Na(+),K(+)-ATPase have been analyzed by co-immunoprecipitation and covalent cross-linking. In detergent-solubilized membranes from HeLa cells expressing both gamma and CHIF
Claudia Simon et al.
The Journal of biological chemistry, 289(15), 10411-10418 (2014-02-26)
VP1 is the major coat protein of murine polyomavirus and forms virus-like particles (VLPs) in vitro. VLPs consist of 72 pentameric VP1 subunits held together by a terminal clamp structure that is further stabilized by disulfide bonds and chelation of
Kimberly L W Schultz et al.
Journal of virology, 89(1), 48-60 (2014-10-17)
Susceptibility to alphavirus infection is age dependent, and host maturation is associated with decreased virus replication and less severe encephalitis. To identify factors associated with maturation-dependent restriction of virus replication, we studied AP-7 rat olfactory bulb neuronal cells, which can
Pål A Olsvik et al.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 165, 17-27 (2014-06-01)
This study aimed to investigate whether dioxin (TCDD) and methylmercury (MeHg) pose a threat to offspring of fish exposed to elevated concentrations of these chemicals via epigenetic-based mechanisms. Adult female zebrafish were fed diets added either 20 μg/kg 2,3,7,8 TCDD
Noriko Himori et al.
Journal of neuroscience research, 92(9), 1134-1142 (2014-05-07)
Although axonal damage induces significant retinal ganglion cell (RGC) death, small numbers of RGCs are able to survive up to 7 days after optic nerve crush (NC) injury. To develop new treatments, we set out to identify patterns of change
Bijay Singh et al.
Biomaterials, 59, 144-159 (2015-05-15)
Orally delivered proteins or antigens are taken up by epithelial microfold cells (M cells) in Peyer's patches, especially abundant in the ileum of small intestine. However, several barriers including gastric pH, enzymatic degradation, rapid transit and lack of specificity of
Jun Hyung Lim et al.
Small (Weinheim an der Bergstrasse, Germany), 11(28), 3469-3475 (2015-03-25)
The use of ZnO nanorods (NRs) as an effective coordinator and biosensing platform to create bioluminescence resonance energy transfer (BRET) is reported. Herein, a hydrothermal approach is applied to obtain morphologically controlled ZnO NRs, which are directly bound to luciferase
Yue Xu et al.
International journal of clinical and experimental medicine, 7(12), 4997-5003 (2015-02-11)
Evaluate the behavior and function of human umbilical vein endothelial cells (HUVECs) on decellularized extracellular matrix (ECM) deposited by bone marrow mesenchymal stem cells (BMSCs). Prepared through chemical approach, decellularized ECM was characterized by use of immunofluorescence staining. The morphology
Karin Kettisen et al.
Bioconjugate chemistry, 26(4), 746-754 (2015-03-04)
Developing a functional blood substitute as an alternative to donated blood for clinical use is believed to relieve present and future blood shortages, and to reduce the risks of infection and blood type mismatching. Hemoglobin vesicle (HbV) encapsulates a purified
Xiefan Fang et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 307(12), R1471-R1487 (2014-10-31)
Previous studies demonstrated that in utero caffeine treatment at embryonic day (E) 8.5 alters DNA methylation patterns, gene expression, and cardiac function in adult mice. To provide insight into the mechanisms, we examined cardiac gene and microRNA (miRNA) expression in
Sam Eggins et al.
Environmental toxicology and chemistry, 34(12), 2771-2781 (2015-09-22)
Total mercury (Hg) concentrations of muscle, liver, blood, and epidermal keratin were measured in typically consumed, economically and culturally important species of turtle (Podocnemis unifilis and Podocnemis expansa) and caiman (Melanosuchus niger and Caiman crocodilus) from the Rio Purus in
L-cysteine functionalized gold nanoparticles for the colorimetric detection of Hg2+ induced by ultraviolet light
Chai F
Nanotechnology, 21(2), 025501-025501 (2009)
Takao Tobe et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 20(4), 687-694 (2015-03-19)
Selenium (Se) is an essential antioxidative micronutrient but can exert cancer-selective cytotoxicity if the nutritional levels are too high. Selenodiglutathione (GSSeSG) is a primary Se metabolite conjugated with two glutathione (GSH) moieties. GSSeSG has been suggested to be an important
Chen Shochat et al.
Blood, 124(1), 106-110 (2014-05-03)
Gain-of-function somatic mutations introducing cysteines to either the extracellular or to the transmembrane domain (TMD) in interleukin-7 receptor α (IL7R) or cytokine receptor-like factor 2 (CRLF2) have been described in acute lymphoblastic leukemias. Here we report noncysteine in-frame mutations in
John B Jonnalagadda et al.
Journal of biomaterials science. Polymer edition, 26(7), 401-419 (2015-02-12)
In this study, poly(e-caprolactone)/polyglycolic acid (PCL/PGA) scaffolds for repairing articular cartilage were fabricated via solid-state cryomilling along with compression molding and porogen leaching. Four distinct scaffolds were fabricated using this approach by four independent cryomilling times. These scaffolds were assessed
Sun-Young Park et al.
Korean journal for food science of animal resources, 35(5), 615-621 (2016-01-14)
Lactobacillus plantarum FH185 was isolated from the feces of healthy adults. In our previous study, L. plantarum FH185 was demonstrated that it has anti-obesity effect in the in vitro and in vivo test. In order to determine its potential for
Surya P Manandhar et al.
The Journal of biological chemistry, 289(16), 11431-11442 (2014-03-13)
Palmitoylation at cysteine residues is the only known reversible form of lipidation and has been implicated in protein membrane association as well as function. Many palmitoylated proteins have regulatory roles in dynamic cellular processes, including membrane fusion. Recently, we identified
Mechanisms of aspirin-intolerant asthma: identifying inflammatory pathways in the pathogenesis of asthma.
Helen Neighbour
International archives of allergy and immunology, 163(1), 1-2 (2013-11-20)
Brian C Wengerter et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(7), 1375-1387 (2014-04-01)
Effective therapeutic vaccines often require activation of T cell-mediated immunity. Robust T cell activation, including CD8 T cell responses, can be achieved using antibodies or antibody fragments to direct antigens of interest to professional antigen presenting cells. This approach represents
Kris M Weigel et al.
Current protocols, 1(7), e209-e209 (2021-07-28)
The gut microbiome is recognized as a critical regulator of human diseases. Constituents of the microbiota and their individual activities can affect a broad range of disease states related to autoimmunity, cancer, infection, metabolism, mental health, and toxicant exposure. A
Elena Geromichalou et al.
European journal of medicinal chemistry, 96, 47-57 (2015-04-16)
Recent science evidenced the interlinkage of oxidative stress and cancer. Due to the inherent complexity of cancer and its accompanying effect of oxidative stress, novel molecules, containing combinatorial functionalities should be targeted. Herein, we synthesized gemcitabine-5'-O-lipoate derived from a regioselective
Frank J Piscotta et al.
Cell reports, 36(12), 109746-109746 (2021-09-23)
The human microbiota plays a critical role in host health. Proper development of the infant microbiome is particularly important. Its dysbiosis leads to both short-term health issues and long-term disorders lasting into adulthood. A central way in which the microbiome interacts
Tanzila Mukhtar et al.
The EMBO journal, 41(24), e111132-e111132 (2022-11-09)
The cerebral cortex contains billions of neurons, and their disorganization or misspecification leads to neurodevelopmental disorders. Understanding how the plethora of projection neuron subtypes are generated by cortical neural stem cells (NSCs) is a major challenge. Here, we focused on
Sun-A Cho et al.
Toxicology letters, 225(1), 185-191 (2013-12-24)
Cosmetics are normally composed of various ingredients. Some cosmetic ingredients can act as chemical haptens reacting toward proteins or peptides of human skin and they can provoke an immunologic reaction, called as skin sensitization. This haptenation process is very important
Hongli Mao et al.
Colloids and surfaces. B, Biointerfaces, 126, 63-69 (2014-12-30)
Three-dimensional (3D) porous collagen sponges incorporated with single-walled carbon nanotubes (SWCNTs) were prepared and used for 3D culture of bovine articular chondrocytes (BACs). The pore structures of the sponges were controlled by using ice particulates as a porogen material. The
S Kaleem Ahmed et al.
Bioorganic & medicinal chemistry letters, 21(14), 4358-4362 (2011-06-15)
Evidence was acquired prior to suggest that the vesicular glutamate transporter (VGLUT) but not other glutamate transporters were inhibited by structures containing a weakly basic α-amino group. To test this hypothesis, a series of analogs using a hydantoin (pK(a)∼9.1) isostere
Page 2 of 17