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Showing 1-30 of 379 results for "469300" within Papers
Mukund Gupta et al.
Nature communications, 6, 7525-7525 (2015-06-26)
Matrix rigidity sensing regulates a large variety of cellular processes and has important implications for tissue development and disease. However, how cells probe matrix rigidity, and hence respond to it, remains unclear. Here, we show that rigidity sensing and adaptation
Muhammad Azeem et al.
Fungal biology, 119(8), 738-746 (2015-08-01)
The pine weevil Hylobius abietis is a severe pest of conifer seedlings in reforestation areas. Weevils lay eggs in the root bark or in the soil near roots of recently dead trees and cover the eggs with frass (feces combined
Alessandra Colombini et al.
Tissue engineering. Part A, 21(3-4), 793-802 (2014-09-23)
The intervertebral disc (IVD) presents a limited self-repair ability and cell-based therapies have been suggested to prevent or treat IVD lesions. Fibrin-based scaffolds as cell carriers are promising candidates in IVD tissue engineering, thanks to their ability to be easily
N Z Piety et al.
Vox sanguinis, 109(3), 221-230 (2015-04-23)
The morphology of red blood cells (RBCs) deteriorates progressively during hypothermic storage. The degree of deterioration varies between individual cells, resulting in a highly heterogeneous population of cells contained within each RBC unit. Current techniques capable of categorizing the morphology
O Estrada-Leypon et al.
Bioelectrochemistry (Amsterdam, Netherlands), 105, 56-64 (2015-05-26)
We describe the design, construction, and characterization of a scalable microfluidic platform that allows continuous monitoring of biofilm proliferation under shear stress conditions. Compared to other previous end-point assay studies, our platform offers the advantages of integration into multiple environments
Francesco E Angilè et al.
Langmuir : the ACS journal of surfaces and colloids, 30(42), 12610-12618 (2014-09-30)
Microbubbles are used as contrast enhancing agents in ultrasound sonography and more recently have shown great potential as theranostic agents that enable both diagnostics and therapy. Conventional production methods lead to highly polydisperse microbubbles, which compromise the effectiveness of ultrasound
Prisila Mkenda et al.
PloS one, 10(11), e0143530-e0143530 (2015-11-26)
Plants with pesticidal properties have been investigated for decades as alternatives to synthetics, but most progress has been shown in the laboratory. Consequently, research on pesticidal plants is failing to address gaps in our knowledge that constrain their uptake. Some
Li Li et al.
Journal of proteomics, 120, 44-57 (2015-03-11)
To elucidate the mechanisms contributing to fruit responses to senescence and stressful environmental stimuli under low temperature (LT) and controlled atmosphere (CA) storage, a label-free quantitative proteomic investigation was conducted in strawberry (Fragaria ananassa, Duch. cv. 'Akihime'). Postharvest physiological quality
Wasina Thakhiew et al.
Journal of food science, 79(6), E1150-E1158 (2014-06-04)
An idea of using a suitable drying method to minimize the loss of added antimicrobial agent and, at the same time, to modify the structure, and hence the release characteristics of chitosan films was proposed. Chitosan film-forming solution was incorporated
Laura Delgado-Moreno et al.
Aquatic toxicology (Amsterdam, Netherlands), 165, 129-135 (2015-06-04)
Natural waters such as surface water and sediment porewater invariably contain dissolved organic matter (DOM). Association of strongly hydrophobic contaminants (HOCs) with DOM leads to decreased toxicity and bioavailability, but bioavailability of DOM-sorbed HOCs is difficult to measure. Current methods
Natinan Bunyakul et al.
Analytical and bioanalytical chemistry, 407(3), 727-736 (2014-06-25)
Sample preparation and processing steps are the most critical assay aspects that require our attention in the development of diagnostic devices for analytes present in complex matrices. In the best scenarios, diagnostic devices should use only simple sample processing. We
Giangiacomo Beretta et al.
Journal of pharmaceutical and biomedical analysis, 98, 144-152 (2014-06-11)
In this study we have analysed the chemical composition of the extractable components from the elastomeric shells from n=27 explanted implants (n=16 patients), n=2 new PIP implants, and from explanted Eurosilicone and McGhan implants (n=2 for each brand). Empty elastomeric
Maxime Boulet-Audet et al.
Analytical chemistry, 86(19), 9786-9793 (2014-09-16)
The use of biotherapeutics, such as monoclonal antibodies, has markedly increased in recent years. It is thus essential that biotherapeutic production pipelines are as efficient as possible. For the production process, one of the major concerns is the propensity of
Na Li et al.
Cellular and molecular life sciences : CMLS, 72(15), 2973-2988 (2015-03-27)
Influenza viruses account for significant morbidity worldwide. Inflammatory responses, including excessive generation of reactive oxygen and nitrogen species (RONS), mediate lung injury in severe influenza infections. However, the molecular basis of inflammation-induced lung damage is not fully understood. Here, we
Ágnes M Móricz et al.
Journal of chromatography. A, 1422, 310-317 (2015-10-27)
Two tansy (Tanacetum vulgare L.) essential oils were obtained by steam distillation of the capitula with subsequent liquid-liquid extraction (oil 1) or with use of an auxiliary phase for the trapping of the steam components (oil 2). These oils were
Alexandra J Dickinson et al.
Analytical and bioanalytical chemistry, 406(27), 7027-7036 (2014-07-02)
Sphingosine kinase (SK) is a promising therapeutic target in a number of cancers, including leukemia. Traditionally, SK has been measured in bulk cell lysates, but this technique obscures the cellular heterogeneity present in this pathway. For this reason, SK activity
Jin-Sil Kim et al.
Food chemistry, 189, 108-113 (2015-07-21)
The aim of this study was to analyse and reduce furan in various model systems. Furan model systems consisting of monosaccharides (0.5M glucose and ribose), amino acids (0.5M alanine and serine) and/or 1.0M ascorbic acid were heated at 121°C for
Cheng Wang et al.
Biosensors & bioelectronics, 71, 222-229 (2015-04-29)
This paper presents an aptameric graphene nanosensor for detection of small-molecule biomarkers. To address difficulties in direct detection of small molecules associated with their low molecular weight and electrical charge, we incorporate an aptamer-based competitive affinity assay in a graphene
Marisol Correa-Ascencio et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(39), 14223-14228 (2014-09-17)
Although in modern societies fermented beverages are associated with socializing, celebration, and ritual, in ancient times they were also importa`nt sources of essential nutrients and potable water. In Mesoamerica, pulque, an alcoholic beverage produced from the fermented sap of several
Volker F Achterberg et al.
The Journal of investigative dermatology, 134(7), 1862-1872 (2014-03-29)
Changes in the mechanical properties of dermis occur during skin aging or tissue remodeling and affect the activity of resident fibroblasts. With the aim to establish elastic culture substrates that reproduce the variable softness of dermis, we determined Young's elastic
Hoseok Choi et al.
Biosensors & bioelectronics, 73, 93-99 (2015-06-09)
We report a simple method for analyzing sequential phosphorylation by protein kinases using fluorescent peptide substrates and microfluidic isoelectric focusing (μIEF) electrophoresis. When a dye-labeled peptide substrate was sequentially phosphorylated by two consecutive protein kinases (mitogen-activated protein kinase (MAPK) and
Peter A Galie et al.
Cytotherapy, 16(7), 906-914 (2014-04-10)
Myocardial infarction results in the formation of scar tissue populated by myofibroblasts, a phenotype characterized by increased contractility and matrix deposition. Mesenchymal stromal cells (MSC) delivered to the myocardium can attenuate scar growth and restore cardiac function, though the mechanism
Andrea Pavesi et al.
Scientific reports, 5, 11800-11800 (2015-07-03)
Stem cell research has yielded promising advances in regenerative medicine, but standard assays generally lack the ability to combine different cell stimulations with rapid sample processing and precise fluid control. In this work, we describe the design and fabrication of
Ljupcho Prodanov et al.
Biotechnology and bioengineering, 113(1), 241-246 (2015-07-15)
The development of long-term human organotypic liver-on-a-chip models for successful prediction of toxic response is one of the most important and urgent goals of the NIH/DARPA's initiative to replicate and replace chronic and acute drug testing in animals. For this
Joe Z Sostaric et al.
The journal of physical chemistry. B, 111(12), 3298-3303 (2007-03-29)
High-power ultrasound (20 kHz) was used to encapsulate a solution of perchlorotriphenylmethyl triester (PTM-TE, a stable organic free radical) dissolved in hexamethyldisiloxane (HMDS) into a polymerized shell of bovine serum albumin (BSA). The size distribution of the microspheres was between
J C Beaulieu et al.
Food chemistry, 181, 354-364 (2015-03-22)
Colorful antioxidant-rich fruits often convey astringency and sourness that juice consumers may not appreciate. We assessed properties in juices from a collection of California-grown pomegranate from the National Clonal Germplasm Repository. The goal was to evaluate overall differences in germplasm
T Bharathidasan et al.
ACS applied materials & interfaces, 7(33), 18450-18459 (2015-08-08)
We developed a single-step thermal method that enables successful inclusion of ZnO components in the porous boron-carbon-nitrogen (BCN) framework to form a new class of functional hybrid. ZnO-containing BCN hybrids were prepared by treating a mixture of B2O3, glycine, and
Igor Jerković et al.
Chemistry & biodiversity, 12(7), 1047-1056 (2015-07-15)
The present study is focused on the antioxidant capacity and chemical profiling of eight Croatian Satureja montana L. honey samples. Among the 20 compounds obtained by headspace solid-phase microextraction (HS-SPME) and identified by GC-FID and GC/MS analyses, hotrienol was predominant
João M Leça et al.
Analytica chimica acta, 887, 101-110 (2015-09-01)
Vicinal diketones, namely diacetyl (DC) and pentanedione (PN), are compounds naturally found in beer that play a key role in the definition of its aroma. In lager beer, they are responsible for off-flavors (buttery flavor) and therefore their presence and
John B Crowe et al.
Journal of forensic sciences, 60(4), 1078-1084 (2015-03-19)
Suspect hypodermic needles and syringes were seized from an unlicensed individual who was allegedly injecting patients with silicone (polydimethylsiloxane [PDMS]) for cosmetic enhancement. Since control syringe barrels and needles often contain an interfering PDMS lubricant, a risk for false positives
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